Madokotala otchedwa Antimulylerov odziwika kale kwambiri, koma mothandizidwa, adaphunzira kuzindikira mavuto ena a chiberekero, atsimikizire kugonana komanso akulosera kuti akuyamba kusamba. Kawirikawiri, kusanthula kwa AMG kumaperekedwa ndi azimayi a zachipatala-otchedwa endocrinologist pa nthawi yoyamba yopanda chithandizo chosowa pogwiritsa ntchito chithandizo chamakono (IVF, insemination). Mankhwala a antimulylerov - chizindikiro chochititsa mantha, kulankhula za kukhalapo kwa matenda aakulu.
AMG mwa amuna ndi akazi
Hormone ya Antimiller (AMG) ndi glycoprotein yokhudzana ndi kukula. Zinthu izi zimayamba kupangidwa pa nthawi ya kukula kwa emmoni: M'nyamata amtsogolo - pa masabata 7-8, ndi atsikana amtsogolo - pamasabata 32-36 a mimba.Ndiyi hormone yomwe imayambitsa mapangidwe a abambo: motsogoleredwa ndi AMG, chiberekero cha m'mimba chimakhala ndi kusintha kwabwino kwa ma mullerian - zizindikiro za chiberekero cha mtsogolo ndi ziphuphu zamasiye. Pambuyo pa kubadwa kwa anyamata m'thupi, mahomoni akupitirizabe kupangidwa mowonjezereka ndi maselo a sertoli, ndipo panthawi yoyamba msinkhu mlingo wa antimulylerovoy hormone wachepa kwambiri.
Azimayi a AMG amapanga maselo a granulosa ovary kuchokera pa 3 trimester ya mimba asanayambe kusamba. Poyerekeza ndi amuna, zomwe zili m'thupi la antimulylerovaya m'magazi a chiwopsezo chofooka ndi otsika kwambiri, ndipo atatha msinkhu, msinkhu wa AMH umachepa pang'onopang'ono. Nchifukwa chiyani izi zikuchitika?
Kawirikawiri, mkazi aliyense pa kubadwa amakhala ndi mazira, omwe pakutha pang'onopang'ono amatha kudya. Pa nthawi ya kusamba, ma follicles angapo amamera kamodzi pa ovary, imodzi yomwe (yaikulu) idzakhala dzira lokhwima. Pa siteji inayake ya kusasitsa kwa maselo a majeremusi, mahomoni a antimulyler amapangidwa omwe amachititsa kukula kwa follicles. Asayansi apeza kuti mlingo wa AMG umalumikizana mwachindunji ndi chiwerengero cha mazira omwe angathe. Kotero, mothandizidwa ndi ATM, wina akhoza kulingalira malo osungira ovoda a mkazi ndikupeza zokhudzana ndi kuyamba kwa kusamba.
Antimulylerov mahomoni amakulira - zifukwa
Kawirikawiri mlingo wa hormone ya antimulylerovoy mwa amuna ndi 0,49-5,98 ng / ml, chifukwa cha kugonana kwabwinoko ndizomwe zikufanana ndi 1-2.5 ng / ml. Inde, pali zochepa zazing'ono kuchokera ku chizoloŵezi. Mwachitsanzo, pa mlingo wa anti-Muller wa 3 mg / mg, musadandaule. Komabe, m'mayi ena antimulylerov hormone yawonjezeka kwambiri: chikhalidwe cha AGM chingakhale 5-6, ndipo nthawizina 9 ng / ml. Kodi chifukwa cha zizindikiro zoterezi ndi chiyani?
Madokotala anapeza kuti mwa akazi antimulylerov hormone pamwamba pa zozolowereka zimagwirizana ndi kukhalapo kwa polycystic mazira, komanso ndi granulosa selo chotupa cha ovary. Kuonjezera apo, AMG yapamwamba ikhoza kusonyeza normogonadotropic endocrine (ovulala) osabereka kapena kuchedwa kwa chitukuko cha kugonana. AMG pamwamba pachibadwa
Kwa amuna, ma hormone ochulukirapo amalankhula za cryptorchidism (malo a mayesero kunja kwa phokoso), kuchedwa ku chitukuko cha kugonana, zolepheretsa kupanga androgens ndi zovuta zina za chiberekero.
Komabe, nthawi zambiri AMG yapamwamba imasonyeza kupezeka kwa matenda. Nthawi zina mkhalidwe wa wodwalayo umakhudza kwambiri zotsatira za phunziro: nkhawa, matenda aakulu, masewera olimbitsa thupi angakhudze mlingo wa magazi m'magazi. Choncho, masiku atatu musanayambe kusanthula, nkofunika kutsogolera moyo wamtendere, kupeŵa chisokonezo ndi kupewa zizoloŵezi zoipa ngati nkotheka.