Gilbert's syndrome - zizindikiro

Matenda a Gilbert's (Gilbert's disease, malaŵi osagwirizana ndi chiwawa, banja losavuta kuzimitsa thupi, matenda ovomerezeka a malamulo) ndi matenda obadwa nawo omwe amachititsa kuti thupi likhale lopweteka, chifukwa cha kusintha kwa jeni lomwe limayambitsa kusokoneza bilirubin m'chiwindi. Nthendayi inatchulidwa ndi gastroenterologist wa ku France Augustine Nicolas Gilbert, yemwe adalongosola poyamba mu 1901. Matenda a Gilbert nthawi zambiri amadziwika kuti ndi bilirubin m'magazi, jaundice ndi zizindikiro zina zomwe sizowopsa ndipo sizikusowa chithandizo mwamsanga.

Zizindikiro za Gilbert's Syndrome

Zizindikiro zazikulu za matendawa zikuphatikizapo izi:

1. Jaundice, pamene poyamba anawona icteric kudetsa za sclera ya diso (kuchokera pafupifupi imperceptible kutchulidwa). Nthawi zambiri, pangakhale kusungunuka kwa khungu kansalu katatu, mitengo ya kanjedza, nsonga.
2. Kusokonezeka mu hypochondrium yolondola, nthawi zina, pangakhale kuwonjezeka pang'ono kwa kukula kwa chiwindi.
3. Kufooka kwathunthu ndi kutopa.
4. Nthawi zina, kusokonezeka, kusokonezeka, matenda osokoneza bongo, kusagwirizana ndi zakudya zina zimachitika.

Chifukwa cha Gilbert's syndrome ndi chiwindi mu chiwindi cha mapuloteni apadera (glucuronyltransferase), omwe amachititsa kusinthanitsa kwa bilirubin. Zotsatira zake, ndi 30 peresenti yokha ya mankhwalawa ndi thupi, ndipo mavitamini amatha kuwonjezereka m'magazi, zomwe zimayambitsa matendawa.

Kuzindikira kwa Gilbert's Syndrome

Matenda a Gilbert's syndrome amapezeka pamayesero a magazi:

1. Chiwerengero cha bilirubin m'magulu a Gilbert kuyambira 21 mpaka 51 μmol / l, koma chikhoza kuwonjezeka mpaka 85-140 μmol / l poyesa kuchita mwakuthupi kapena matenda ena.
2. Chitsanzo ndi njala. Amayesa zovuta zenizeni (osati zachilendo) kwa matenda a Gilbert. Posiyana ndi kusala kudya kapena kutsata m'masiku ochepa a zakudya zamadzimadzi, bilirubin m'magazi akukwera ndi 50-100%. Ziyeso za bilirubin zimagwiritsidwa ntchito m'mimba yopanda kanthu musanayese mayesero, ndiyeno pambuyo pa masiku awiri.
3. Chitsanzo ndi phenobarbital. Pogwiritsa ntchito phenobarbital, mlingo wa bilirubin m'magazi umatsika kwambiri.

Momwe mungakhalire ndi matenda a Gilbert?

Nthendayi yokhayo saonedwa kuti ndi yoopsa ndipo kaŵirikaŵiri imafuna chithandizo chamankhwala. Ngakhale kuchuluka kwa bilirubin m'magazi kumapitirirabe m'moyo wonse, koma msinkhu wake woopsa sufikira pawopsya. Zotsatira za chizindikiro cha Gilbert kawirikawiri zimangokhala kuwonetsera kunja ndikusokonezeka pang'ono, motero, kuphatikizapo kudya, mankhwalawa amagwiritsira ntchito kokha matenda a hepatoprotectors kuti apangitse chiwindi kugwira ntchito. Komanso (nthawi zambiri, mankhwala akuluakulu a mankhwalawa) amatenga mankhwala osokoneza bongo omwe amathandiza kuchotsa mtundu wobiriwira wa thupi.

Kuonjezera apo, zizindikiro za matenda sizakhala zamuyaya ndipo nthawi zambiri zimatha kukhala zosazindikirika, kuwonjezeka ndi kuwonjezera thupi, kumwa mowa, njala, chimfine.

Chinthu chokha chomwe chingakhale chowopsa ndi Gilbert's syndrome - nthawi zambiri, ngati boma silingalemekezedwe ndi matenda, zimathandiza kuti kutukula kwa biliary ndi cholelithiasis zikule .

Ndipo ziyenera kukumbukiridwa kuti matendawa ndi ofanana, choncho ngati pali mbiri ya mmodzi wa makolo, ndi bwino kuti mufunsane ndi jiniyo musanayambe kukonza mimba.