Allopurinol ndi mafananidwe ake ndi mankhwala omwe amaperekedwa ndi kuchulukitsa uric acid mu thupi - hyperuricemia. Nthendayi imayambitsa matendawa. Mankhwala amalimbikitsidwa kwa odwala omwe sangathe kulamuliridwa ndi zakudya zokha.
Mapiritsi a Allopurinol amaperekedwanso kwa anthu omwe ali ndi matenda a miyala ya urate ndi nephropathy. Amagwiritsidwa ntchito kwa akuluakulu ndi ana oposa zaka khumi ndi zisanu ndi zisanu (15) omwe ali ndi zizindikiro za matendawa kumbuyo kwa khansa ya m'magazi , komanso anthu omwe ali ndi vuto loperewera m'mimba.
Kodi mungasinthe bwanji Allopurinol ndi gout?
Zithunzi zofanana za Allopurinol:
- Zonse;
- Alopron;
- Sanphipurol.
Chigawo chachikulu ndi oxypurinol, chomwe chimalepheretsa kutembenuka kwa hypoxanthine ku xanthine, ndiyeno ku uric acid. Mothandizidwa ndi mankhwala osokoneza bongo, msinkhu wa mkodzo mumtsinje ndi dongosolo lozungulira limachepa. Izi zimalepheretsa kulemera kwa makina amchere mu thupi ndikulimbikitsa resorption yawo. Kuchuluka kwa asidi kumayamba kuchepa pa tsiku lachinayi la kumwa mankhwala. Mphamvu yapamwamba imatha pambuyo pa milungu iwiri.
Purinol imakhalanso analog yomangidwa ya Allopurinol. Panthawi ya kayendetsedwe ka mankhwalawa, kaphatikizidwe ka uric acid imachepa, zomwe zimapangitsa kuchepa kwa madzi omwe akuwonetsa thupi. Kuonjezera apo, ma deposit omwe kale alipo amatha kusungunuka ndipo mapangidwe awo opangidwanso mu impso ndi matendawa amaletsedwa. Pogula Purinol, chitetezo cha xanthine ndi hypoxanthine mu mkodzo chikuwonjezeka. Zotsatira za mankhwalawa zimadalira mlingo woyenera.
Contraindications kwa ntchito Allopurinol ndi zifaniziro zake
Allopurinol ndi mafananidwe ake, omwe amalembedwa kuti akhale gout , ali ndi zotsutsana zambiri, zomwe zimawonetseredwa m'mabuku amodzi. Kotero, mwachitsanzo, panali odwala omwe anayamba bradycardia ndi matenda oopsa. Nthawi zina, panali:
- kunyoza ndi kusanza;
- kutsekula m'mimba;
- chiwindi;
- mphutsi;
- steatorrhea.
Pafupi nthawi zonse izi zinkayenda ndi:
- kufooka;
- kufooka kwakukulu;
- mutu;
- ataxia;
- chizungulire.
Nthawi zocheperapo - kuphwanya masomphenya ndi masamba, kukoma kwa ubongo, kupwetekedwa mtima, kupsinjika maganizo ndi chiwerewere.
Panthawi yachipatala, odwala omwe anali ndi vuto la khungu, hyperemia, pruritus, malungo ndi malungo ankawonetsanso. Nthawi zina, anthu amapanga furunculosis ndi tsitsi lofiira.
Ngati kuli kotheka, akatswiri amalimbikitsa kutenga Allopurinol yokha, ndipo ngati mukufuna kuikamo ndi chinachake, muyenera kugwiritsa ntchito zilembo zamtengo wapatali. Apo ayi, izo zingasokoneze kwambiri ntchito ya chiwindi ndi thupi lonse lathunthu.