Estradiol ndi hormone ya steroid, yomwe imapangidwa makamaka m'mimba mwa mazira ndi maonekedwe okhwima a adrenal gland mwa akazi. Estradiol ndiyo yothandizira kukula kwa kugonana kwa mtundu wazimayi, kupangika maganizo kwapachikhalidwe kwa amayi. Mchitidwe wa homoni uwu umayendetsedwa ku chiberekero, mazira a mammary, mazira, mazira oyipa.
Mlingo wa estradiol ndiyomweyo
Chizoloŵezi cha estradiol mwa amayi chimasiyana malinga ndi nthawi ya kusamba ndipo ndi:
- 97.5 - 592 pmol / l - chizolowezi cha estradiol mu follicular phase;
- 685-1404 pmol / L ndizozoloŵera za estradiol pachimake chisanafike;
- 120 - 738 pmol / l - chizoloŵezi cha estradiol mu luteal phase;
- 9 - 258 pmol / l - chizolowezi cha estradiol pakutha.
Ethoradiol hormone mwa amuna
Estradiol imapangidwa mu thupi lamwamuna ndi ma testes ndi mawonekedwe a makina a adrenal glands. Estradiol mwa amuna amachititsa kuti maselo a metabolism, kuphatikizapo calcium. Kawirikawiri, mlingo wa homoni iyi mwa amuna ndi 19.7 - 242 pmol / l.
Chikhalidwe cha estradiol mu mimba
Pamene ali ndi pakati komanso pamene ikukula, mlingo wa estradiol mu thupi la mkazi umakula kwambiri. Mpweya wapamwamba wa hormoni uwu umakhalapo asanabwerere, ndipo atatha kubadwa, mlingo wa estradiol umakhala wovomerezeka.
Estradiol pa nthawi yoyembekezera imapangidwa ndi placenta. Mchitidwe wa homoni uwu umayendetsedwa ku chiberekero, zotengera zake, magazi coagulability. Estradiol amateteza mwana wamtsogolo mimba yonse. Mkhalidwe wake ndi:
- 215.0 - 430.0 pg / ml mu trimester yoyamba;
- 800.0 - 576.0 pg / ml mu trimester yachiwiri;
- 1810 - 13,900 pg / ml mu 3 trimester.
Chizoloŵezi cha kusanthula kwa mlingo wa estradiol
Kufufuza pa mlingo wa estradiol kumaperekedwa pofuna kudziwa momwe matenda akuyendera komanso kusabereka. Masiku atatu asanatuluke mayesero sakuvomerezeka kuchita zolimbitsa thupi. Kufufuza kumaperekedwa pa mimba yopanda kanthu.
Estradiol pamwamba pachibadwa
Mlingo wa estradiol pamwamba pa chizolowezi ukhoza kuwonedwa ndi zizindikiro zotere:
- kupitiriza kwa follicle;
- endometrioid cysts ya mavava;
- chotupa cha mahomoni cha m'mimba mwake;
- isrogenosecretizing chotupa cha testicular;
- chiwindi cha chiwindi.
Estradiol pamapeto a chikhalidwe
Mlingo wa hormone wa estradiol ukhoza kuchepetsedwa ndi:
- zochita masewera olimbitsa thupi akazi osaphunzitsidwa;
- kusuta;
- hypogonadism;
- hyperprolactinemia;
- kusakwanira kwa mahomoni a gawo la luteal;
- choopsya chochotsa mimba ya endocrine genesis.
Estradiol kwa IVF
Estradiol imapangitsa kukula kwa endometrium, komwe kuli kofunika podutsa njira ya IVF ndi feteleza. Mlingo wa estradiol utatha kutengapo mimba ndi chizindikiro chofunikira cha mimba yabwino. Mlingo wa estradiol umayesedwa pa tsiku loyambitsirana m'mimba ndipo patapita sabata. Pamalo ochepa a estradiol, chithandizo cha mahomoni chamthupi chimaperekedwa, chomwe chimaonetsetsa kuti chitukuko chimakula bwino.