Ntchito zoteteza chitetezo m'thupi zimapanga chitetezo chokwanira. Njirayi imasiyanitsa mitundu yapadera ya mapuloteni a magazi - ma immunoglobulins osiyanasiyana. Selo yotetezera E imateteza majekeseni kuchokera ku zinthu zomwe zimapangitsa kuti munthu asatengeke.
Nchifukwa chiyani immunoglobulin ikuwonjezeka, ndipo amatanthauzanji?
Kupanga chithunzithunzi cha chitukuko cha hypersensitivity ndi chakuti pamene matupi a thupi amayamba kugwirizana ndi zomwe zimapangitsa kuti thupi liziyenda bwino, amayamba kudziunjikira m'deralo. Pamene kuyambitsa zinthu kumachita ndi maselo a mapuloteni, kutukuka kumaloko kumachitika chifukwa cha kutuluka kwakukulu kwa histamines ndi zigawo zina za cytotoxic. Chifukwa chake, pali zizindikiro monga:
- rhinitis;
- Kuthamanga kwa mucous membrane ndi khungu pamwamba;
- chitsulo;
- mphumu;
- anaphylactic mantha .
Choncho, ngati immunoglobulin E ikukwera, zinthu zowopsya zimalowetsa thupi ndipo zimakhala zosavomerezeka, zomwe zimadzaza ndi kutupa kwamba, zimayamba kukula.
Kodi kuchuluka kwa immunoglobulin E kwa akuluakulu kumatanthauza chiyani?
Monga lamulo, patatha zaka khumi 12 mapuloteni omwe ali m'kati mwake sali ofunikira kwambiri. Kwa akuluakulu, ma immunoglobulin a m'kalasi E amawonjezeka chifukwa chogwirizana ndi thupi nthawi zonse, ndipo zizindikiro (zachibadwa) za chizindikiro ichi m'magazi zimachokera ku 20 mpaka 100 IU / l. Zikatero, ngakhale hypersensitivity amphamvu kwa mtundu uliwonse wa zosakaniza zosakondweretsa sikuwongolera kuwonjezeka kwakukulu kwa mapuloteni ambiri omwe amatetezedwa. Chiwerengero cha immunoglobulin E chikhoza kuwonjezeka kokha ngati pali zovuta zowonjezera mndandanda waukulu wa histamines komanso kuphatikizapo mphumu yakufa. Nthawi zina, zotsatira za mayeso a labotolo zimapangitsa kuti matendawa akhale ochepa chabe pa odwala akuluakulu.
Tiyenera kuzindikira kuti kuwonjezeka kwa immunoglobulin E kumachitidwa ndi zilonda zosagwirizana ndi matenda, monga helminthiasis. Nyongolotsi zimasokoneza ziwalo zawo zamkati. Izi zimachititsa kuti chitetezo cha mthupi chitengeke, chomwe chimaphatikizapo kupititsa patsogolo mapuloteni.
Matenda omwe amafotokozedwanso amatha kupangitsa matenda awa:
- immunodeficiency, makamaka congenital;
- chonchi;
- kuphatikiza kwa bronchial asthma ndi dermatitis ndi rhinitis;
- IgE-myeloma.
Kuonjezerapo, kukhazikitsa chidziwitso choyenera sikokwanira kudziwa momwe maginito a immunoglobulins amachitira mtundu wa E. Kuwonjezereka kwa magazi n'kofunikira kuti mudziwe ma antibodies enieni (pafupifupi 600).
Chiwerengero cha immunoglobulin E ndi zomwe zimayambitsa zochitikazi zawonjezeka kwambiri
Kawirikawiri mu zotsatira za kafukufuku wa labotale amtengo wapatali kwambiri wa mapuloteni a chitetezo cha m'thupi amatsimikiziridwa, kuyambira 2 mpaka 50,000 IU / l. Pafupifupi zenizeni zitha kutsimikiziridwa kuti munthu yemwe ali ndi vutoli akudwala matenda a hyper-IgE-syndrome.
Matendawa ndi a ma genetic pathologies ndipo amatsatiridwa ndi zizindikilo:
- chibayo;
- ziphuphu pa khungu ndi mucous membrane;
- mobwerezabwereza rhinitis ndi kutupa kwa khutu;
- kuchepa kwa mafupa, kutsekula kwa m'mimba, kuphulika kwa miyendo yaŵirikaŵiri;
- kusuntha kwakukulu kwa ziwalo zazikulu;
- chithandizo;
- sinusitis;
- nkhungu zofala za mtundu wa Candida;
- dermatitis ya atopic;
- matenda opatsirana mano;
- matenda ;
- Kusintha kwa nkhope nkhope (mphuno, mphuno, kubzala kwakukulu kwa maso, chinkhuku chachikulu, kupitilira patsogolo).