Mtengo ndi madzi ofiira obiriwira otetezedwa ndi chiwindi (hepatocytes) mosalekeza.
Bulu yambiri imasonkhanitsidwa mu bile ducts, ndipo kuchokera pamenepo imalowa mu gallbladder ndi duodenum, kumene imatenga mbali yogwira ntchito. Malingana ngati bile ikuyenda pamtumbo, ambiri amamwa zakudya zam'mimba, ndipo ena onse amachotsedwa thupi limodzi ndi nyansi.
Ngati ntchito ya kupanga bile chifukwa chapachifukwa chilichonse, matenda a chiwindi ndi nyongolotsi amayamba kudwala, kuwonjezera, chimbudzi chimachepa. Pachifukwa ichi, perekani zokonzekera choleretic, mndandanda ndi mndandanda wa mawonekedwe omwe mumalowa m'malo mwake, tidzayesa pansipa.
Mankhwala osokoneza bongo
Kusiyanitsa cholagogue amatanthauza:
- chiyambi cha atitchoku, tansy, mizu ya burdock, chimanga cha chimanga, mizu ya dandelion, masamba a nettle, immortelle, etc.);
- kupanga.
Malinga ndi momwe amachitira (pharmacodynamics), mndandanda wa zokonzekera zamakono zamakono ndizowonjezereka, koma zonsezi zikhoza kuphatikizidwa m'magulu awiri:
- Choleretics - kulimbikitsa mapangidwe a bile acid (LC) ndi bile.
- Cholekinetics ndi cholespismolytics - yongolerani excretion ya bile mu duodenum polimbikitsa kupopera kwa gallbladder kapena mosiyana kupuma sphincter Oddi ndi musculature wa bile ducts.
Izi zimakhala zofunikira, popeza zambiri zomwe zikukonzekera cholagogue zimapangitsanso kusintha kaphatikizidwe ka kapangidwe ka bile.
Choleretics
Gulu ili la mankhwala osokoneza bongo, komanso, lili ndi zotsatirazi.
Choleretics weniweni ndi mankhwala osokoneza bongo, omwe makamaka amachititsa kuti chitetezo cha bile ndi lactic acid chiwonjezeke. Mankhwalawa angathe:
- lili ndi LCD (Holenzim, Allochol, Vigheratin, etc.);
- kupanga (Nikodin, Oxafenamid, Tsikvalon, Odeston, etc.);
- ali ndi chilengedwe (Tanachevol, Holosas, Flakumin, Convaflavin, etc.);
Mankhwala osokoneza bongo ndi mankhwala omwe amawonjezera kuchulukitsa bile ndi maselo a chiwindi chifukwa cha chigawo cha madzi. Mwa gululi, zokonzekera bwino za cholagogue zimayimilidwa ndi madzi amchere (Jermuk, Essentuki No. 17, No. 4, Izhevskaya, etc.), sodium salicylate ndi valerian-based products.
Kukonzekera kwa gululi kumaperekedwa kwa matenda aakulu a chiwindi; Kuphwanya kuphulika kwa bile (dyskinesia ya bile ducts). Ngati kuli koyenera, mankhwalawa akuphatikizidwa ndi maantibayotiki, laxatives, analgesics.
Cholekinetics ndi choleospasmolytics
Kwa zinthu, zotsatira zake zimapereka kuwonjezeka kwa kamvekedwe ka ndulu ndi ducts (cholekinetics), kuphatikizapo:
- sulfate ya magnesiamu;
- cholecystokinin;
- kukonzekera pogwiritsa ntchito barberry ;
- mannitol;
- choleritin;
- pituitrin;
- sorbitol;
- xylitol.
Kukonzekera kotereku kumasonyezedwa kwa chronic cholecystitis, kuphwanya kwa outflow ya bile (dyskinesia), atony wa gallbladder, matenda aakulu a chiwindi.
Zinthu zomwe zimamasula minofu ya bile ndondomeko (holespazmolitiki):
- mbale;
- atropine;
- iodide ya metocinium;
- kuchotsa belladonna;
- aminophylline;
- papaverine;
- drotaverine;
- mebeverin;
- olimine.
Gawoli la zokonzekera choleretic ndi lothandiza kwa cholelithiasis ndi dyskinesia ya hyperkinetic mawonekedwe.
Samalani
Perekani mankhwala omwe adatchulidwa ayenera kukhala dokotala yekha, monga momwe ntchito yawo ikusiyana. Mwachitsanzo, kukonzekera kwa giardiasis, komanso kupweteka kwa matenda, cholecystitis , matenda a hepatitis adzakhala osiyana. Choncho, kudzipiritsa kungangowonjezera chithunzi cha matendawa.