Chorionic gonadotropin ndi hormone kuchokera ku gulu la glycoprotein, lomwe limasonyeza kuyamba kwa mimba mu thupi lachikazi. Kuwoneka mu mkodzo wa chorionic gonadotropin pathupi ndikufotokozera maonekedwe awiri. Pofufuza kukula kwa chorionic gonadotropin pa nthawi ya mimba, n'zotheka kuweruza momwe mimba imayambira.
Chorionic gonadotropin mu mimba ndi yachilendo
Kawirikawiri, akazi ndi amuna omwe alibe amayi, β-hCG mndandanda wa 0-5 mU / ml. Mtengo wa chorionic gonadotropin umayamba kuwonjezeka kale m'masiku oyambirira mutatha kukhazikika kwa mluza mu chiberekero cha uterine. Amapangidwa ndi matenda a chorion ndipo amachitanso mbali yofunikira pa nthawi yomwe ali ndi mimba. Choncho, chorionic gonadotropin imalimbikitsa mapangidwe a placenta, komanso imathandiza kuti thupi lachikasu lizichita bwino (kupanga homoni ya progesterone ). Pambuyo pa chigawochi, zimatengera ntchito yokonza chorionic gonadotropin.
Kumayambiriro kwa mimba, masiku awiri kapena atatu, chizindikiro cha h-hchch (chorionic gonadotropin) chawonjezeka kawiri. Kuyambira pa sabata la 10-11 la mimba, chiwerengero cha kukula kwa hCG chikucheperachepera, pamene pulasitala yayamba kupangidwa ndikuyamba kugwira ntchito yotulutsa mahomoni a mimba. Choncho, m'masabata oyambirira a mimba, mlingo wa chorionic gonadotropin m'magazi uli ndi 25-156 mU / ml. Mbali ya gonadotropin ya chorionic 1000 mU / ml ikufanana ndi sabata lachitatu la mimba. Pa masabata 4-5 ichi chiwerengero ndi 2560-82300 mU / ml, pamasabata 7-11 pambuyo pathupi mlingo wa chorionic gonadotropin m'magazi amakafika 20900-291000 mU / ml, ndipo pakadutsa masabata 11-12 amatha kuchepa kwa 6140-103000 mU / ml.
Chorionic gonadotropin ili ndi magauni awiri - alpha ndi beta. Manambala a alpha ali ofanana mofanana ndi mahomoni omwe amachititsa kansalu-stimulating, luteinizing ndi follicle. Bungwe la beta ndi lapadera kwambiri.
Gonadotropin chorionic - ntchito
Gonadotropin ya chorionic yaumunthu imagwiritsidwa ntchito pochiza infertility (kukakamiza ovulation ndi in vitro fetereza, kusamalira ntchito ya chikasu thupi). Chorionic gonadotropin kwa amuna akulamulidwa kuti azilimbikitsa spermatogenesis ndi kupanga androgens (nthawizina amagwiritsidwa ntchito masewera monga doping).
Kugwiritsiridwa ntchito kwa chorionic gonadotropin kumasonyezedwa m'mabvuto otsatirawa:
- mwa amayi omwe ali ndi chiwerengero chokwanira cha luteal (kuti athandize ovulation ndi kukhala ndi mphamvu ya chikasu thupi);
- mwa amuna omwe ali ndi matenda opitilira chitukuko, anachedwa kutha msinkhu, hypogonadotropic hypogonadism.
Mankhwala a gonadotropin chorionic amatsutsana pamene:
- ziphuphu za kugonana, komanso zina zomwe zimayambitsa kugwidwa kwa gonads;
- cryptorchidism yowonongeka ndi chilakolako chachikazi, kupweteka ndi opaleshoni;
- kusagwirizana pakati pa chorionic gonadotropin.
Kodi mungakonde bwanji chorionic gonadotropin?
- Njira ya chorionic gonadotropin imapezeka ngati jekeseni. Majekeseni opatsirana a gonadotropin amasungunuka bwino ndipo amachitika malinga ndi zomwe adokotala adalamula.
- Zowopsa zowonongeka zitha kuzindikiritsidwa kuwonjezeka kwa mavitcosity a magazi ndi mavuto omwe amapezeka nawo, kuphatikizapo matenda a ovarian hyperstimulation. Anyamata angathe kukulitsa msanga maseŵera awo am'mimba, akhoza kukula ndi kutupa.
Tinafufuza ntchito ya chorionic gonadotropin mu thupi la mayi wapakati, komanso amadziŵa momwe amagwiritsira ntchito mafananidwe ake.