Glucocorticosteroid ndi chinthu chachilengedwe kapena chiyambi. Imatanthawuza ku chigawo cha mahomoni mu adrenal cortex. Kukonzekera kuchokera ku gulu la glucocorticosteroids kumakhala ndi zotsatira zowonongeka komanso kumapanga mapangidwe a shuga pachiwindi, choncho amagwiritsidwa ntchito pochiza matenda osiyanasiyana.
Kodi glucocorticosteroids imakhudza bwanji thupi?
Chofunika kwambiri cha chilengedwe cha glucocorticosteroids ndi kuwonjezera kwambiri kukanika kwa thupi. Mankhwalawa amagwiritsidwanso ntchito kuthetsa chiwawa cha chitetezo cha mthupi, chomwe chimayikidwa pa thupi lake. Matendawa amapezeka pamene thupi limatuluka, zilonda zopweteka komanso matenda ena. Kuonjezera apo, glucocorticosteroids imakhudza mchere, madzi, mavitamini komanso mapuloteni. Amagwiritsidwanso ntchito ngati anti-inflammatory, antitoxic ndi desensitizing agents. Mankhwalawa angagwiritsidwe ntchito ngati mankhwalawa:
- malonda;
- parenteral;
- inhaled glucocorticosteroids.
Mankhwalawa amatha kutulutsa magazi. Zimakwaniritsidwa chifukwa cha kuchuluka kwakukulu kwa kutulutsidwa kwa adrenaline, komanso kuchepa kwa mitsempha ya mitsempha. Izi zimapangitsa kugwiritsa ntchito glucocorticosteroids kuthana ndi zizindikiro zoopsya muzovuta kwambiri.
Maina a mankhwala osokoneza bongo kuchokera ku gulu la glucocorticosteroids
Pali zochepa zokonzekera kuchokera ku gulu la glucocorticosteroids, ndipo mayina ena a iwo amadziwika bwino ndi anthu ambiri, chifukwa amagwiritsidwa ntchito pochiza matenda ofala. Zida zotchuka kwambiri za mtundu uwu:
- Belogen - kirimu kapena mafuta opangira kunja. Amagwiritsidwa ntchito pa chizungu , kufalitsa matenda a neurodermatitis, atopic ndi zina zotupa.
- Sherisolone - mapiritsi omwe ali okhudzana ndi zowonongeka glucocorticosteroids. Ankachiza matenda a scleroderma , nodular periarteritis, nyamakazi ya nyamakazi.
- Cortonisol ndi aerosol yomwe imagwiritsidwa ntchito ku colitis, matenda a Crohn, proctitis ndi ulcerative colitis.
- Solu Medrol ndi lyophilizate yokonzekera yankho kapena kuyimitsa madzi kwa jekeseni. Amagwiritsidwa ntchito powotcha ndikugwedezeka, zovuta zowonongeka.
Aliyense mankhwala kuchokera mndandanda wa glucocorticosteroids ali ndi contraindications. Mmodzi mwa iwo sayenera kugwiritsidwa ntchito pa matenda a shuga, Cushing matenda, thromboembolism ndi kulephera kwakukulu kwa chiwindi. Sikoyenera kuchita mankhwala ndi glucocorticosteroids panthawi yogwiritsira ntchito chifuwa chachikulu cha TB.