Mahomoni a hypothalamus

Hypothalamus ndi imodzi mwa ziwalo zikuluzikulu m'thupi la munthu. Ili pafupi ndi ubongo. Iye ali ndi udindo woyenera wa chigoba cha pituitary ndi kagayidwe kake kachibadwa. Mahomoni opangidwa mu hypothalamus ndi ofunika kwambiri kwa thupi. Ndi mapeptidi omwe amachititsa njira zosiyanasiyana zochitika m'thupi.

Kodi ndi mahomoni otani omwe amapangidwa ndi hypothalamus?

Mu hypothalamus muli maselo a mitsempha, omwe amachititsa kupanga mahomoni onse ofunikira. Amatchedwa maselo a neurosecretory. Panthawi inayake, amalandira maganizo okhudzidwa, omwe amaperekedwa ndi mbali zosiyanasiyana za dongosolo la manjenje. Mankhwala a neurosecretory maselo amathera pamitsinje ya magazi, kumene amapanga axo-vasal synapses. Kupyolera mu mahomoni otsiriza ndi opangidwa ali osakanizidwa.

The hypothalamus imapereka ma liberin ndi maonekedwe - otchedwa kutulutsa mahomoni. Zinthu izi zimafunika kuti muyambe kuyendetsa mankhwala opangira mahomoni. Statins ndi omwe amachititsa kuchepetsa kaphatikizidwe ka zinthu zomwe zimadziimira okha, komanso liberiya kuti liwonjezere.

Mpaka pano, mahomoni opambana kwambiri a hypothalamus:

1. Gonadoliberines. Mahomoni amenewa ali ndi udindo wowonjezera kuchuluka kwa mahomoni opatsirana pogonana. Amachitanso nawo kuthandizira pa nthawi ya msambo komanso kupanga chilakolako cha kugonana. Mothandizidwa ndi kuchuluka kwa lyuliberin - imodzi mwa mitundu ya gonadotype - masamba okhwima a dzira. Ngati mahomoni awa sali okwanira, mkazi akhoza kuyamba kusabereka .
2. Somatoliberin. Mahomoni awa, opangidwa ndi hypothalamus, amafunika kuwamasula kukula kwa zinthu. Ayenera kukhala otchuka kwambiri mu ubwana ndi unyamata. Ngati mulibe homoni, zimakhala zochepa.
3. Corticoliberin. Chifukwa cha kuchuluka kwa mavitamini a adrenocorticotropic mu nthiti ya pituitary. Ngati mahomoni sangapangidwe muyeso yofunikira, nthawi zambiri vutoli limakhala losavomerezeka.
4. Prolactoliberin. Thupili limakhudzidwa kwambiri makamaka mukakhala ndi pakati komanso nthawi yonse ya lactation. Chotsulo ichi chimapangitsa kuchuluka kwa prolactini komwe kumatulutsa ndi kulimbikitsa chitukuko cha mazira m'mimba.
5. Dopamine, melanostatin ndi somatostatin. Amapezetsa mahomoni otentha omwe amapangidwa m'kamwa.
6. Melanoliberin. Amathandizira kupanga melanin ndi kubereka kwa maselo a pigment.
7. Tyroliberin. Ndikofunikira kudzipatula mahomoni otulutsa chithokomiro ndikuwonjezera thyroxine m'magazi.

Kukonzekera kwa kutsekemera kwa mahomoni a hypothalamus

Mitsempha ya mitsempha imayankha ku lamulo la kusokonezeka kwa mahomoni. Mahomoni ochulukirapo amatha kutulutsa makina otentha kwambiri, otchedwa hormone otentha kwambiri. Ubale umenewu sungangokhala wokhumudwitsa. Nthaŵi zina, zimasintha zotsatira za mahomoni a hypothalamus pa maselo omwe ali m'mimba ya pituitary.

Mankhwala opanga mahomoni a hypothalamus

Izi zikuphatikizapo:

1. Sermorelin. An analogue ya chilengedwe kukula hormone. Amapatsidwa makamaka kwa ana omwe ali aang'ono kwambiri. Zimaletsedwa panthawi ya mimba komanso panthawi yopuma.
2. Bromocriptine. Anayamba kulimbikitsa mapuloteni a dopamine. Amaperekedwa kuti asokoneze lactation.
3. Zosangalatsa. Zingathe kuchepetsa kukula kwa mahomoni okula komanso kulepheretsa ntchito ya minofu yambiri. Amaperekedwa kwa zilonda zam'mimba ndi kubisa zotupa.
4. Rifatiroin. Chifaniziro cha mahomoni a hypothalamus a tiropropin.
5. Stylamine. Ikhoza kuchepetsa kuthamanga kwa magazi mkati mwa ziwalo za mkati, popanda kuthandizira dongosolo la bloodic systemic.