Clavulanic acid ndi chinthu chapadera chimene chimagwirizana ndi penicillinases ndipo chimayambitsa. Zitha kuwonedwa mwazimene zimagwiritsidwa ntchito pamodzi ndi mankhwala osokoneza bongo. Komanso, clavulanic acid ingagwiritsidwe ntchito mofanana ndi mankhwala a beta-lactam.
Njira yogwiritsira ntchito clavulanic asidi
Akatswiri amanena kuti achula ya clavulanic imayambitsa matenda. Thupi limeneli limatha kupanga mankhwala amphamvu kwambiri. Mankhwala omwe ali ndi clavulanic acid amasonyezedwa kuti agwiritsidwe ntchito pa matenda osiyanasiyana opweteka owopsa chifukwa cha mavairasi owopsa ndi mabakiteriya.
Mapangidwe a mamolekyu a clavulanic acid ndi ofanana ndi maantibayotiki a mndandanda wa penicillin. Ichi ndi chifukwa chake kuphatikiza kwawo kuchokera kumaganizo akuwonedwa ngati kupambana. Kusiyana kwakukulu ndikuti mu asidi mmalo mwa thiazolidine pali mphete ya oxazolidine. Koma kugwirizana kwa zinthu sikunakhudzidwe konse.
Kulowa m'thupi, clavulanic acid imaletsa beta-lactamase - mabakiteriya, maonekedwe ake omwe amachititsa ntchito yofunikira ya tizilombo towononga. Kawirikawiri, mfundo ya kugwira ntchito ya clavulanic acid ndi yosavuta: kudzera mu chipolopolo chotetezera, imalowa mkati mwa maselo a mabakiteriya ndipo "imachotsa" mavitamini omwe ali mkati. Choncho, mankhwalawo salola kuti mavairasi ndi mabakiteriya azichulukana.
Monga momwe adasonyezera, pambuyo poletsa, kuchepetsa beta-lactamase kumaonedwa kuti n'zosatheka. Chifukwa cha tizilombo ta tizilombo toyambitsa matenda sitingathe kukhalanso, koma timataya mwayi wotsutsa ma antibiotic omwe amawakhumudwitsa.
Mphamvu ya chinthucho ndi yaikulu kwambiri. Ngakhale mabakiteriya ndi mavairasi omwe atha kukhala ndi chitetezo choteteza Amoxicillin ndi Ampicillin amawonongedwa ndi ntchito ya clavulanic acid. Izi zikutanthauza kuti kuchuluka kwa mankhwala osokoneza bongo kumakhala kwakukulu kwambiri kuposa ma antibayotiki ambiri.
Kwenikweni, mankhwala osokoneza bongo ndi clavulinic acid amatengedwa pamlomo, koma nthawi zina, ma intravenous administration amaonedwa kuti ndi othandiza. Zomwe zili choncho, palibe zotsutsana za mankhwalawa, si oyenera okha kwa odwala omwe alibe tsankho. Pa milandu yovuta kwambiri, a clavulic acid kuphatikizapo Amoxicillin ndi Ticarcillin amatha kutengedwa ngakhale ndi amayi apakati.
Augmentin - Amoxicillin ndi clavulanic acid
Ichi ndi chimodzi mwa mankhwala odziwika bwino omwe amadziwika ndi maantibayotiki. Mankhwalawa akuwonetsedwa ndi zoterezi:
- bronchitis (kuphatikizapo mawonekedwe osatha);
- chibayo;
- kupuma kwa mapapo ;
- matenda opatsirana;
- cystitis;
- peritonitis;
- osteomyelitis;
- angina;
- septicemia;
- pyelonephritis.
Mlingo wa Augmentin kwa wodwala aliyense wasankhidwa payekha, malinga ndi mawonekedwe ndi zovuta za matendawa, mkhalidwe wa wodwala, msinkhu wake, wogwirizana ndi matenda. Chithandizo ndi mankhwala ayenera kukhala osachepera asanu, koma osapitirira masiku khumi ndi anayi.
Flemoxin ndi clavulanic acid
Uwu ndiwo mgwirizano wotchuka kwambiri wotchedwa Flemoklav. Wothandizira wabwino wa antibacterial amawononga pang'ono kuposa Flemoxin yapachiyambi, koma mtengo wake ndi wolondola ndi mphamvu zake.
Chida chimagwiritsidwa ntchito pochita njira zosiyanasiyana zotupa:
- otitis;
- pharyngitis ;
- chitsulo;
- chibayo;
- matenda opatsirana pogonana;
- kupweteka kwa dermatological;
- matenda opatsirana komanso opweteka mafupa ndi ziwalo.
Flemoklav imatulutsidwa ngati mapiritsi osungunuka, chifukwa chakuti mphamvu zake zimakula kwambiri.