Mu minofu yambiri, kuphatikizapo mtima, komanso mitsempha, impso, airways ndi zina zina, pali beta-adrenergic receptors. Iwo ali ndi udindo pa zovuta, ndipo nthawizina zoopsa, thupi limapangitsa kugonjetsa ndi kupanikizika ("kugunda kapena kuthamanga"). Pofuna kuchepetsa ntchito zawo zamankhwala, beta-blockers amagwiritsidwa ntchito - mndandanda wa mankhwala ochokera ku gulu la mankhwalawa ndi lalikulu kwambiri, zomwe zimalola kusankha mankhwala abwino kwambiri kwa wodwala aliyense payekha.
Osasankha beta-blockers
Pali mitundu iwiri ya adrenoreceptors - beta-1 ndi beta-2. Pamene kusiyana koyamba kutsekedwa, zotsatira zotsatirazi za mtima zimapindula:
- kuchepetsa chiwerengero cha mtima ndi nthawi;
- kuchepetsa kuthamanga kwa magazi;
- kuponderezedwa kwa kuperewera kwa mtima.
Ngati mumaletsa beta-2-adrenoreceptors, pali kuwonjezereka kwa kumbuyo kwa mitsempha ya magazi ndi mawu:
- chiberekero (mwa amayi apakati);
- chitsulo;
- arterioles.
Kukonzekera kuchokera ku kagulu ka nonselective beta-blockers sichichita mwachindunji, kuchepetsa ntchito ya mitundu yonse ya ma receptors.
Mankhwala otsatirawa amatchula mankhwala omwe akugwiritsidwa ntchito:
- Oxprenolol;
- Propranolol;
- Pindolol;
- Anaprilin;
- Sotalol;
- Penbutolol;
- Nadolol;
- Timolol;
- Chonchi;
- Obsidan;
- Bopindolol;
- Zochita-E;
- Mchenga;
- Levobunolol;
- Wistagen;
- Korgard;
- Obinol;
- Wistagan;
- Oxprenolol;
- Tracicore;
- Koretal;
- Vickin;
- Sotalol;
- Timolol;
- Viskaldix;
- Sotagexal;
- Okumol;
- Sotaleks;
- Arutimol;
- Xalacom;
- Zoyim;
- Fotil ndi ena.
Kusankha beta-blockers
Ngati mankhwalawa akugwiritsidwa ntchito mosachepera komanso amachepetsa kugwira ntchito kwa beta-1-adrenergic receptors yekha, ndizofuna kusankha. Ndikoyenera kudziwa kuti mankhwala oterowo ndi ofunika kwambiri pamatenda a mtima wamtima, pambali pake, amakhala ndi zotsatira zochepa.
Mndandanda wa mankhwala osokoneza bongo kuchokera ku gulu la cardioselective beta-blockers la mbadwo watsopano:
- Phokoso;
- Atenolol;
- Khumi;
- Prinorm;
- Bisoprolol;
- Tenoric;
- Hypoten;
- Bisocardium;
- Tenoretik;
- Bisogamma;
- Chithunzi;
- Lokren;
- Chithunzi;
- Betaxolol;
- Metoprolol;
- Phokoso;
- Corvitol;
- Vasocardine;
- Logimax;
- Egilok;
- Metocard;
- Amzok;
- Osati tikiti;
- Esmolol;
- Breviblock;
- Nebivolol;
- Talinolol;
- Cordanum;
- Acebutolol.
Zoipa za beta-blockers
Zochitika zolakwika nthawi zambiri zimayambitsa mankhwala osasankha. Izi zikuphatikizapo zifukwa zotsatirazi:
- bongo ;
- zizindikiro za mtima kulephera;
- choyimitsa;
- ululu m'chifuwa;
- kusokonezeka kugona kapena kusowa tulo;
- chizungulire;
- kukhumudwa ndi kukumbukira;
- kupweteka;
- ziwonetsero zooneka ndi zozizwitsa;
- mphamvu yogwira ntchito;
- kusamvera;
- mutu;
- chisokonezo;
- mkamwa wouma;
- kutsekula m'mimba kapena kudzimbidwa;
- kusanza;
- ululu pa epigastrium ndi matumbo;
- kusokonezeka kwa minofu;
- bronchospasm;
- dyspnea;
- kupuma kovuta;
- kupweteka kwa magazi;
- thrombocytopenic purpura;
- chithandizo;
- chithandizo;
- kuchepetsa libido ndi potency;
- gynecomastia;
- minofu yamtundu;
- chithandizo ;
- chisokonezo;
- myasthenia gravis;
- kuuma kwa mucosa diso;
- kuwonetsa;
- kuchepa kwa kuchuluka kwa madzi otsekemera omwe amatulutsidwa;
- conjunctivitis;
- kuyabwa kwa khungu;
- urticaria;
- thukuta lalikulu;
- kukhudzidwa kwa khungu ku ultraviolet;
- chithunzithunzi cha epidermis;
- kubwereranso kwa psoriasis;
- alopecia (kusinthika);
- ululu kumbuyo.
Kawirikawiri, atasiya adrenoblocker, pali "matenda obweretsera" mwa kuwonjezereka kwakukulu ndi kolimba kwa magazi, nthawi zambiri za angina pectoris.