Prolactin ndi hormone yomwe imagwira ntchito mwachindunji mu njira ya ovulation, ndipo imayambitsa kutuluka kwa mkaka wa mawere (lactation) posakhalitsa nthawi. Panthaŵi imodzimodziyo, prolactin imaletsa kupanga hommoni yochititsa chidwi imene imakhalapo pakadali pano. Kusintha kwa mlingo wa prolactin kumapangitsa kuti puloteniyo isapangidwe, ndipo chifukwa chake - kutsekemera sikupezeka. Ndiko kulibe komwe kungakhalenso chizindikiro chochepa cha prolactin mwa amayi, chifukwa chake mkazi sangathe kutenga mimba.
Kodi ma prolactin ambiri mwa akazi amasintha bwanji?
Masana, prolactin imatulutsidwa m'magazi a mkazi osagwirizana. Kotero, mu mankhwala, zimanenedwa kuti kaphatikizidwe ka hormone iyi ndi chirengedwe. Choncho, panthawi yonse ya thupi - kugona, kuika thupi m'thupi kumakula. Ndikumadzuka, imagwa mofulumira ndipo imakhala yochepa m'mawa. Masanasana, ma prolactin amakula.
Komanso, mlingo wa hormoni iyi umadalira mwachindunji gawo la kumapeto kwa msambo. Mwachitsanzo, mu gawo la lutein, mlingo wa hormone m'magazi ndi wapamwamba kusiyana ndi mu follicular phase. Chodabwitsa, hormone iyi ili mu magazi a anthu. Iye ali ndi udindo pazochitika za maphunziro, komanso pokonza bwino spermatozoa, komanso amathandizira kupanga testosterone ndi thupi.
Kuchepetsa prolactin
Monga tanenera kale, ma prolactin ambiri m'thupi sali pambali nthawi zonse ndipo amadalira zinthu zambiri. Choncho, pakakhala zovuta m'mayi, mlingo wa homoni uwu ndi wabwinobwino. Mphalidwe otsika a prolactin mwa amayi amalankhula za kukhalapo kwa thupi la matenda amtundu wina, komanso kumakhudza kwambiri kukonzekera mimba.
Kawirikawiri chiwerengero chochepa cha prolactin mwa amayi chikhoza kusonyeza kukhalapo kwa matenda ngati Shimakh's syndrome. Matendawa amawonetsedwa ndi kuchepa kwa thupi, komwe kawirikawiri amawoneka pamene akumwa magazi pamene akubereka . Kuonjezera apo, kuchepa kwa puloteni m'magazi a mkazi kungakhale chizindikiro cha apoplexy ya gland.
Pulogalamu ya prolactin yochepa pakakhala nthawi yaitali mimba imakhala chizindikiro ndipo kamodzinso ikhoza kutsimikizira pererachivaemost yake.
Prolactin wotsika akhoza kukhala ndi zotsatira za kumwa mankhwala, mwachitsanzo, antihistamines, anticonvulsants, ndi morphine.