Zollinger-Ellinson Syndrome

Dzinali lovuta kwambiri limakhala la chotupa. Mofananamo, mkhalidwe wa thanzi pamaso pa chotupa. Matenda a Zollinger-Ellison amapezeka kuti ali ndi chotupa chachikulu, nthawi zambiri - duodenum kapena m'mimba. Zizindikiro za matendawa nthawi zambiri zimasokonezeka ndi zilonda za m'mimba, chifukwa cha zomwe mankhwalawa sakuperekedwa nthawi. Kudziwa za matendawa, mungapewe mavuto aakulu okhudzana ndi matendawa. Za izi ndikuyankhula mu nkhaniyi.

Zollinger-Ellison matenda

Vuto lalikulu ndilo kuti odwala ambiri ali ndi matenda a Zollinger-Ellison omwe amasonyeza zizindikiro zofanana ndi zilonda zam'mimba . Choncho, mayesero onse ndi kafukufuku amachitidwa mofanana. Ndikofunika kumvetsetsa kuti gastrinomas - zotupa zomwe zimapezeka mu matenda a Zollinger-Ellison - nthawi zambiri zimakhala zoipa. Ndipo pakakhala choncho, mukudziwa, simungathe kupirira. Ngakhale kuti gastrinomas imakulitsa kukula kwake pang'onopang'ono, akhoza kuyamba metastases ku ziwalo zoyandikana nawo, kuwonjezera vuto limodzi.

Mpaka pano, ndizozoloŵera kusankha matendawa motere:

1. Single gastrinomas, yomwe nthawi zambiri imakhala pamakina.
2. Ziphuphu zambiri zingathe kufalikira ku makanda, komanso ngakhale kupyolera m'mimba.

Matenda a hypergermemia amatha kukhalapo pamaso pa chithokomiro, zilonda za adrenal, ndipo amachititsidwa kuti ndiye chifukwa chachikulu cha maonekedwe a matenda a Zollinger-Ellison.

Zizindikiro zazikulu za matendawa

Kawirikawiri odwala omwe ali ndi matenda a Zollinger-Ellison kutsogolo kwa matenda opatsirana, zilonda zam'mimba zimakula. Choncho, makamaka, zizindikiro za matenda ndizofanana. Mawonetseredwe aakulu a matendawa amawoneka ngati awa:

1. Chizindikiro chachikulu mu matenda a Zollinger-Ellison ndi amphamvu, kawirikawiri ndi ululu wautali pamwamba pa mimba.
2. Msuzi ayenera kuyambitsa kupweteka kwa mtima ndi asidi kukoma m'kamwa, komwe kumawonekera pambuyo pa njira.
3. Wodwalayo amalemerera kwambiri.
4. Chenjezo liyenera kulipidwa komanso khalidwe la mpando. Kutsegula m'mimba mobwerezabwereza, zitsulo zamakono ndi zizindikiro zofunika za matenda.
5. Kawirikawiri, mu matenda a Zollinger-Ellison, reflux isophagitis imayamba, zomwe zimayambitsa chisokonezo ndi maonekedwe a mthethe.
6. Ngati nthendayi yadutsa mudziko losanyalanyaza, pangakhale chiwindi cha chiwindi.

Mukapeza chimodzi mwa zizindikirozi za matenda a Zollinger-Ellison, muyenera kuthamangira kukaonana ndi dokotala. N'zosakayikitsa kuti zokayikitsa sizolondola, koma kufufuza kwakukulu sikungakhale kovuta.

Kuchiza kwa matenda a Zollinger-Ellison

Kuti mudziwe zilonda zomwe zinkawonekera chifukwa cha matenda a Zollinger-Ellison, muyenera kuwona zovuta zonse. Izi zidzakuthandizani kupeŵa zolakwika zachipatala ndikuthandizira kuika mankhwala othandiza.

Chofunika kwambiri cha chithandizo cha matenda a Zollinger-Ellison ndicho makamaka kuchotsa chotupacho. Pachifukwachi, mutatha opaleshoni, ndikofunika kuti muwone momwe ziwalo zakhudzidwa ndi ziwalo zilili pafupi. Ndikoyenera kukhala okonzekera kuti pa nthawi ya opaleshoni, metastases yomwe imachokera ku chotupa imapezeka nthawi zambiri, chifukwa chake osapitirira 30% amachiritsidwa kwathunthu.

Thandizo kwa thupi panthawi yachipatala (ndi nthawi zina m'moyo wake wonse) lingathe mankhwala odabwitsa omwe amachepetsa kuchuluka kwa hydrochloric acid.

Mwamwayi, maulosi a Zollinger-Ellison matenda amawoneka abwino kwambiri kuposa ena otupa oopsa. Ngakhale pamaso pa metastases, odwala amatha kuchira ndikugonjetsa malo omwe akukhalapo zaka zisanu.