Bacteriophages - Mitundu ndi cholinga

Njira yokhayo yogwiritsira ntchito mankhwala opha tizilombo kuchokera ku mabakiteriya a tizilombo mpaka lero ndi mapiritsi kapena bacteriophages. Ndi mavairasi enieni omwe amasankha mitundu yosiyanasiyana ya tizilombo toyambitsa matenda. Magulu angapo amadziwika kuti amachiza, omwe mabakiteriophages amagawanika - mitundu ndi cholinga cha tizilombo ting'onoting'ono timapanga maziko a chikhalidwe chovomerezeka.

Kodi bacteriophages ndi chiyani?

Pali mabanja 19 a mavairasi omwe akufunsidwa. Iwo amasiyana ndi mtundu wa nucleic acid (RNA kapena DNA), mawonekedwe a genome ndi mawonekedwe.

M'chipatala, bacteriophages amagawidwa malinga ndi kuchuluka kwa chiwonongeko cha tizilombo toyambitsa matenda:

1. Chosavuta. Vutoli, kulowa m'maselo a tizilombo toyambitsa matenda, limayamba kuwonjezeka mofulumira, pafupifupi nthawi yomweyo imatsogolera ku imfa ya mabakiteriya (lytic effect).
2. Okhazikika. Bacteriophages pang'onopang'ono ndi kuwononga kokha mapangidwe a tizilombo toyambitsa matenda, koma amachititsa kusintha kosasinthika mwa iwo, komwe kumafalitsidwa kwa mibadwo yotsatira ya tizilombo toyambitsa matenda (lysogenic effect).

Masiku ano, mitundu yambiri ya mavairasi amagwiritsidwa ntchito ngati njira zina zochiza ma antibayotiki pofuna kuchiza matenda osiyanasiyana a bakiteriya. Zina mwa ubwino wawo, ndizofunika kuwona zotsatirazi:

1. Njira yabwino yomasula. Bacteriophages amapangidwa m'mapiritsi komanso ngati njira yothetsera mauthenga.
2. Zotsatira zochepa zochepa. Mosiyana ndi maantibayotiki, bacteriophages sichimayambitsa mawonetseredwe owopsa, samabweretsa zotsatira zovulaza thupi.
3. Kusasowa kwa tizilombo toyambitsa matenda. Mabakiteriya ndi ovuta kuwongolera mavairasi, ndipo zovuta zimakhala zosatheka.

Pali zovuta zina:

• mankhwala otalikitsa (mpaka masiku 20);
• zovuta ndi kusankha gulu labwino la mankhwala;
• kutumiza kachirombo ka bakiteriya kuchokera ku tizilombo toyambitsa matenda kupita ku chimzake.

Mitundu ya bacteriophages ndi ntchito yawo

Chifukwa cha mavairasi omwe akufotokozedwa, mankhwala, mabakiteriophages ambirimbiri ovuta komanso ovuta omwe ali ndi mitundu ingapo ya tizilombo ting'onoting'ono timakonda.

Pano, kodi bacteriophages - ndondomeko ndi ndondomeko iti:

1. Mimba. Zowawa zimakhudza tizilombo toyambitsa matenda a typhoid fever, salmonella.
2. Dysfag, kamwazi kambirimbiri. Amagwiritsidwa ntchito kwa mitsempha ya bakiteriya, imayambitsa imfa ya Shigella Sonne ndi Flexner.
3. Klebsifag, Klebsiella chibayo. Amathandizira kuchiza matenda a urogenital, kudya, kupuma, matenda opatsirana, matenda opatsirana omwe amachititsidwa ndi chibayo klebsiella .
4. Klebsiellezny zowonjezereka. Ndi mankhwala ovuta omwe amawononga Klebsiella osati chibayo, komanso ma rhinoscleromas, ozena.
5. Colitis, ngati. Kugwiritsa ntchito mankhwala opatsirana aliwonse a ziwalo zamkati ndi khungu chifukwa cha E. coli matenda opatsirana m'magazi E. coli.
6. Coliproteophage, coliprotein. Zimakhudza kwambiri mabakiteriya a tizilombo toyambitsa matenda Proteus ndi Escherichia. Cholinga chake ndi kuchiza matenda a colpitis, cystitis, colitis, pyelonephritis ndi matenda ena opweteka ndi matumbo ndi prost.
7. Proteophagus, Protean. Zimayambitsa imfa ya ma proteus microbes mirabilis ndi vulgaris, zomwe zimayambitsa matenda a purulent inflammatory infections of the intestine.
8. Pseudomonas aeruginosa. Lysers mabakiteriya pseudomonas aeruginosis. Ndikofunika kuti dysbiosis, komanso chithandizo cha kutupa m'mayendedwe osiyanasiyana amtundu wochokera kwa Pseudomonas aeruginosa.
9. Staphylophage, staphylococcus. Amapewa mwamsanga msanga staphylococci, omwe amamasulidwa chifukwa cha matenda ena alionse a purulent.
10. Streptophagus, streptococcal. Mofananamo ndi kachitidwe ka bacteriophage yammbuyo, koma ikugwira ntchito motsutsana ndi streptococci.
11. Intersti. Ndizovuta kukonzekera lysing salmonella, shigella, E. coli , staphylococcus, enterococci, pseudomonas aeruginosa ndi proteus.
12. Piopolyphage, kuphatikiza piobacteriophage. Mankhwalawa ali ofanana ndi mitundu yapitayi, koma imathandizanso kuchokera ku streptococci.
13. Sextapage, pyobacteriophagous polyvalent. Kuwonjezera apo akupha escherichia coli.
14. Chipatala chokwanira. Kusakaniza kwa mapuloteni a entroocci, streptococci, staphylococci, vulgaris ndi mirabilis proteasis, klebsiella oxytoca ndi chibayo, escherichia coli, pseudomonas aeruginosis.