Kuchulukitsa bilirubin - zifukwa

Bilirubin ndi bile pigment, yomwe ndi mankhwala otsalira a kusokoneza maselo ofiira a magazi akale. Kawirikawiri, munthu wachikulire wathanzi m'magazi a m'magazi ali ndi kachilombo kakang'ono (3,4 - 22,2 μmol / l), komanso mkodzo wina monga urobilinogens (4 mg) tsiku ndi tsiku.

Pafupifupi 96 peresenti ya bilirubin m'magazi ndi yosasunthika bilirubin, yomwe imalowerera m'madzi ndipo ndi poizoni, chifukwa Amatha kudutsa mkati mwa maselo osokoneza bongo ndikusokoneza ntchito zofunika kwambiri za maselo. Zotsalira 4% ndi bilirubin yeniyeni, imasungunuka m'madzi, imasankhidwa ndi impso ndikupitirira mu mkodzo. Chiwerengero cha bilirubin ndi chiwerengero cha bilirubin.

Muzirombo zina, zomwe zili mu bilirubin m'magazi, komanso m'kodzo, zimawonjezeka. Izi zimayambitsa jaundice ndi mdima wa mkodzo.

Zomwe zimayambitsa ma bilirubin ndi akuluakulu

Tiyeni tikambirane, chifukwa chake bilirubin wamba kapena munthu wamba amatha kuwonjezeka kapena kuwonjezeka.

Zomwe zimayambitsa kuchuluka kwa bilirubin

Mlingo wa bilirubin mwachindunji m'magazi ukuwonjezeka chifukwa cha kuphwanya kwa kunja kwa bile. Chifukwa chake, bile imatumizidwa ku magazi osati m'mimba. Zifukwa izi ndizo zotsatirazi:

• hepatitis ya tizilombo toyambitsa matenda m'thupi mwachiwindi (hepatitis A, B, ndi matenda opatsirana a mononucleosis);
• hepatitis ya bakiteriya etiology (leptospirosis, brucellosis);
• matenda a chiwindi;
• chithandizo;
• mankhwala amtundu wa hepatitis (chifukwa cha mankhwala a mahomoni, mankhwala osagwiritsa ntchito mankhwala oletsa kutupa, mankhwala osokoneza bongo ndi mankhwala oletsa chifuwa);
• hepatitis (poizoni ndi poizoni, mankhwala oopsa);
• khansa ya gallbladder, chiwindi kapena kapangidwe;
• cholelithiasis;
• biliary cirrhosis;
• syndromes a Rotor, Dabin-Johnson.

Zomwe zimayambitsa kuwonjezeka kwa bilirubin

Kuwonjezeka kwa zinthu zomwe sizikugwirizana ndi bilirubin zingagwirizane ndi chiwonongeko chofulumira cha maselo ofiira ofiira kapena kusokonezeka pakukonzekera kwa bilirubin yosalunjika. Ndikoyenera kuzindikira kuti, kuyambira Bilirubin yosalunjika m'madzi sichitha, ngakhale kuwonjezeka kwakukulu mu msinkhu wake m'magazi, mulibe zopotoka pakusanthula mkodzo. Kotero, zifukwa izi zingakhale:

• Matenda a magazi omwe amachititsa kuti magazi asapitirire kudwala (matenda a sickle, spherocytic, nesferocytic, thallasemia, matenda a Marciyafawa-Michele);
• kupweteka kwa magazi m'thupi (motsutsana ndi nyamakazi ya mafupa, systemic lupus erythematosus, lymphocytic khansa ya m'magazi, lymphanganulmatosis, etc.);
• mankhwala a hemolytic anemia (okhudzana ndi insulini, aspirin, levomycetin, levofloxacin, cephalosporins, etc.);
• syndromes a Lucy-Driskol, Gilbert, Kriegler-Nayyar;
• Matenda opatsirana (malungo, typhoid, sepsis);
• mankhwala oopsa a hemolytic anemia ( poizoni ndi bowa woopsa, poizoni, kuumirira tizilombo, njoka, poizoni ndi bowa, kutsogolera, mchere wa mkuwa, etc.).

Zomwe zimayambitsa kuchulukitsa bilirubin mu mimba

Kuwonjezeka kwa bilirubin kumawoneka mwa amayi omwe ali ndi pakati (jaundice mu mimba). Zifukwa izi zimagawidwa m'magulu awiri:

• chifukwa cha kuchepa kwa mimba (kutaya kwambiri kwa chiwindi, gestosis, kusanza kwakukulu, etc.);
• Chifukwa cha matenda osiyanasiyana omwe amachititsa matendawa (hepatitis, hemolytic anemia, etc.).

Zomwe zimayambitsa kuchulukitsa bilirubin mu mkodzo

Kuchuluka kwa bilirubin mu mkodzo kumawoneka mu matenda omwe amaphatikizidwa ndi kuwonongeka kwa maselo a chiwindi maselo:

• chiwindi;
• chiwindi cha chiwindi ;
• kuwonongeka kwa chiwindi;
• kuvulala kwa chiwindi, etc.

Kuchiza kwa bilirubin yakwezeka

Ngati mayeserowa amasonyeza kuti bilirubin m'magazi kapena mkodzo ndipamwamba, mfundo za chithandizo zimadalira zomwe zimayambitsa matendawa. Kawirikawiri, njira zamankhwala zimaphatikizapo kumwa mankhwala ndi kusintha zakudya.