Mahomoni otchedwa prolactin amatengedwa kwambiri ndi mahomoni opatsirana pogonana. Cholinga chake sichingakhale chodabwitsa kwambiri: prolactin imakhala ndi zotsatira zazikulu kapena zocheperapo pamtundu uliwonse wa machitidwe 300 mu thupi lachikazi.
The prolactin ndi machitidwe ake mwa amayi
Kodi chizoloŵezi cha prolactin mwa akazi ndi chiyani? Palibe yankho lomveka bwino la funsoli, chifukwa malo osiyanasiyana a ma laboratori, chifukwa cha njira zosiyanasiyana zofufuzira, zizindikiro zosiyana zimakhazikitsa mfundo zawo (normative). Kuwonjezera apo, ma laboratories osiyanasiyana amagwiritsa ntchito magulu osiyanasiyana a prolactin.
Zizindikiro zowerengera za msinkhu wamba wa prolactin mwa amai ukhoza kutsimikiziridwa. Choncho, malire a prolactin m'mayi wathanzi komanso opanda amayi sayenera kupitirira pa 4.0-4.5 ng / ml. Pakalipano, monga malire apamwamba ayenera kukhala mkati mwa 23.0-33.0 ng / ml.
Pa nthawi ya kusamba, msinkhu wa prolactin mwa mkazi umasinthasintha, motero, ndipo magulu a ma hormone m'magulu osiyanasiyana a mkanganowo ndi osiyana. Madokotala amalimbikitsa kuti ayese magazi pamayambiriro a msambo (nthawi ya follicular phase). Koma ngati pangakhale pazifukwa zina kumayambiriro kwa kusamba kwake phunziro silinayambe, labotale iliyonse imayambitsa zikhalidwe zake pazigawo zotsatila.
Prolactin ndi hormone yeniyeni kwambiri, mlingo wake ukhoza kusintha pang'onopang'ono, kupsa mtima, pambuyo kugonana, kutsogolo kwa kumwa mankhwala ena, ndipo kumapotoza zotsatira za phunzirolo. Pachifukwa ichi, pofuna kufanizira mozama za chiwerengero cha mahomoni otchedwa prolactin ndi chikhalidwe chake mwa mkazi wobadwa msinkhu, kufufuza kawiri kumalimbikitsa.
Zovuta zoletsa za prolactin: zowonongeka
Chikhalidwe, pamene msinkhu wa prolactin mwa mkazi umakhala pansi pa chizoloŵezi, nthawi zambiri safuna mankhwala. Prolactin ikhoza kuchepa kwambiri chifukwa cha kumwa mankhwala ena, makamaka mankhwala, zomwe cholinga chake poyamba kuchepetsa kupanga maselo omwewo.
Kuwonjezerapo phunziro pofuna kutsimikizira / kusasamala matenda opatsirana ndi kofunika kokha ngati mlingo wa mahomoni ena amatsitsa pansi pa chikhalidwe chokha ndi prolactin.
Kuchulukitsa chiwerengero cha ma prothectin a mahomoni mwa amayi kungakhale zotsatira za masoka m'thupi lake
- (kutenga mimba, nthawi ya kuyamwitsa), ndipo zingasonyeze kupezeka kwa matenda aakulu, monga:
- chotupa chochititsa manyazi cha chifuwa cha pituitary (prolactinoma);
- kutentha kwa chithokomiro (hypothyroidism);
- sycystic ovary syndrome (PCOS);
- chiwindi chachikulu ndi / kapena matenda a impso;
- zotupa za hypothalamus.
Kawirikawiri mkazi saganiza kuti mlingo wa prolactini mu thupi lake ukuwonjezeka, mpaka nthawi yomwe iye sangawone vuto la kulera kwa mwanayo. Mapuloteni apamwamba ndi omwe amachititsa kuti munthu asabereke mwana aliyense wachisanu yemwe wamvapo.
Matenda oyenera a prolactin m'mayi oyembekezera
Mlingo wa prolactini m'mayi oyembekezera nthawi zonse umakweza, izi ndizofunikira. Mahomoni ambiri m'magazi amatha kale pa sabata lachisanu ndi chitatu cha mimba ndipo amatha kufika pamtunda wachitatu. Kuwonjezeka kwa prolactin kumachepetsanso pang'onopang'ono ndipo kumabwerera kumayambiriro ake oyambirira pokhapokha kutha kwa kuyamwitsa.
Malingana ndi zikhalidwe zakhazikitsidwa, mlingo wa prolactin m'mayi oyembekezera uyenera kukhala mkati mwa 34-386 ng / ml (malinga ndi ma laboratories 23.5-470 ng / mg), kukula pang'onopang'ono pa nthawi ya mimba kuchokera kumapeto mpaka kumtunda. Koma madokotala ena amakono amanena kuti palibe chifukwa chokhazikitsira machitidwe a prolactin mwa amayi apakati.
Mayi amodzi ali ndi mahomoni ambiri omwe amatha kusinthasintha, kuphatikizapo prolactin oscillations, nthawi zambiri sagwirizana ndi zizolowezi zilizonse, komabe izi siziri matenda.