Anaprilin ndi mankhwala ochokera ku gulu la beta-blockers limene limasonyeza antianginal, hypotensive ndi antiarrhythmic. Ichi ndi mankhwala abwino kwambiri, otsika mtengo komanso otchipa omwe angathe kuchepetsa msanga mtima komanso kuthamanga kwa magazi, kuthetsa mantha, komanso kuchepetsa vutoli. Komabe, mankhwalawa sali ndi zotsatirapo ndipo angagwiritsidwe ntchito poyang'aniridwa ndi dokotala, ndipo nthawi zina amatsutsana kuti agwiritsidwe ntchito. Kodi pali mafananidwe a Anadrilin opanda zotsatirapo, ndipo ndiwotani, tidzakambirana zambiri.
Zizindikiro za Anaprilin
Mankhwala omwe akukambirana ngati chinthu chachikulu chogwiritsira ntchito ali ndi mankhwala opangidwa ndi propranolol hydrochloride. Mankhwala ofanana ndi a Anaprilin, omwe ali ndi mankhwala ofanana, ndiwo mankhwala otsatirawa:
- Propranolol;
- Obsidan;
- Noloten;
- Posachedwa;
- Pulogalamu;
- Propranolobene;
- BetaCap TR.
Popeza malonda omwe adatchulidwawo ndi ofanana ndi omwe akuwongolera, motero, malinga ndi zizindikiro, zotsutsana ndi zotsatira zake, zimasintha.
Palinso mafananidwe a Anaprilin osati molingana ndi mphamvu yogwira ntchito, i.e. izi ndi mankhwala omwe ali ndi gulu limodzi la mankhwala (beta-blockers) ndi kusonyeza zinthu zomwezo, koma kuphatikizapo zigawo zina zomwe zimagwira ntchito. Kuwonjezera apo, lero pali mankhwala otetezeka omwe ali ndi njira zofanana - zosankha (osankha) beta-blockers. Mankhwalawa, mosiyana ndi Anaprilin osasankha, amaletsa ntchito za mitundu yina ya ziwalo za beta-adrenergic receptor, zomwe zimayenera kuchita. Choncho, palibe zotsatira pa ziwalo zina, ndipo chiwerengero cha zotsatira zowonongeka mu mankhwala ndi mankhwalawa ndi kuchepetsedwa kwambiri.
Mafananidwe amasiku ano a Anaprilin ndi mankhwala otsatirawa:
- Atenolol (Atenobene, Atenova, Ormidol);
- Bisoprolol (Bidop, Concor , Cordinorm);
- Metoprolol (Vazocardin, Serdol, Corvitol);
- Betaxolol (Betac, Lokren, Xonefy);
- Nebivolol (Binelol, Nebivator, Nebival) ndi ena.
Kukonzekera pa mndandanda wa pamwambazi kumasiyana ndi momwe iwo akufunira, nthawi yokwanira, nthawi yowonjezera ndi zizindikiro zina zambiri. Chigamulo cha mankhwalawa chomwe chiyenera kugwiritsidwa ntchito pa chithandizo chingatengedwe ndi dokotala payekha, malinga ndi chidziwitso cha maphunziro opatsirana, zizindikiro za thupi la wodwala ndi kulekerera kwa mankhwala.
Kodi n'zosatheka kuti m'malo mwa Anaprilin mutengere tachycardia pa thyrotoxicosis?
Thyrotoxicosis ndi matenda omwe amayamba chifukwa cha kuchuluka kwa mahomoni a chithokomiro, momwe maselo onse a thupi amathandizira. Odwala omwe ali ndi matendawa nthawi zonse, ngakhale atagona, amakhala ndi nkhawa chifukwa cha kuwonjezeka kwa mtima - tachycardia. Kufunika kwa minofu ya mtima mu oksijeni kumawonjezeka, thupi limagwira ntchito molemetsa. Kuphatikizanso, odwala omwe muli thyrotoxicosis akhoza kuchitika
Ndi matendawa, tachycardia sichichotsedwe ngakhale pamene akugwiritsa ntchito mankhwala osokoneza bongo omwe amawachotsa m'maganizo ena onse - glycosides wamtima (pokhapokha atagwiritsidwa ntchito popanda mankhwala omwe amachepetsa kupanga mahomoni a chithokomiro). Mwamsanga mukhale bwino mkhalidwe wa wodwalayo pakadali pano akhoza Anaprilin (komanso mankhwala ena opangidwa ndi propranolol), zomwe zimachepetsanso kuchuluka kwa mahomoni a chithokomiro T3. Zotsatira za Anaprilin, zokhudzana ndi beta-blockers, zotsatira zake pa tachycardia chifukwa cha thyrotoxicosis sizothandiza. ndalama izi sizitha kuchepetsa chiwerengero cha T3.