Matenda oopsa omwe ali pamtundu umodzi wa adrenal glands kapena ziwalo zina za mitsempha yamatenda amatchedwa pheochromocytoma - zizindikiro za matendawa zimatsimikizira kuchitidwa kwa mahomoni. Amakhala ndi maselo a chromaffin minofu ndi ubongo. Matenda opweteka a mtundu umenewu ndi osowa, pa 10% okha.
Pheochromocytoma - zimayambitsa
Sikudziwika chifukwa chake matendawa amayamba. Pali kukayikira kuti chiwombankhanga chikuwonekera chifukwa cha kusintha kwa majini.
Nthawi zambiri matendawa amakhudza anthu akuluakulu, kuyambira zaka 25 mpaka 50, makamaka amayi. Kawirikawiri, chotupa chimakula mwa ana, ndipo nthawi zambiri chimapezeka mwa anyamata.
Malignant pheochromocytoma nthawi zambiri imakhala pamodzi ndi mitundu ina ya khansara (chithokomiro, m'matumbo, mucous membrane), koma metastases sizomwe zimayendera.
Zizindikiro za pheochromocytoma
Symptomatology imadalira malo a chotupacho, chifukwa chotupa cha adrenal gland chimapanga mitundu iwiri ya mahomoni: adrenaline ndi norepinephrine. Nthawi zina, imapanga norepinephrine yokha. Choncho, zotsatira za pheochromocytoma zidzakhala zooneka bwino ndi malo ake adrenal.
Kuwonjezera apo, zizindikirozo ndi zosiyana ndi mitundu yodziwika ya matendawa, omwe amagawidwa molingana ndi kachipatala:
- paroxysmal;
- nthawi zonse;
- zosakaniza.
Paroxysmal pheochromocytoma - zizindikiro:
- katatu wa Carney (kutengera mtima, kuwonjezeka thukuta, kupweteka mutu);
- Kuwonjezereka kwakukulu ndi mwadzidzidzi kuthamanga kwa magazi kukuimira 300 mm Hg. Art. ndi zina;
- phokoso;
- mantha osadziwika;
- chizungulire;
- ululu pamimba ndi kumbuyo kwa sternum;
- mpweya wochepa;
- chisokonezo;
- chithunzi;
- kuwonetsa;
- kuwonjezeka kwa kutentha;
- kusanza.
Pakuti chizoloŵezi chokhazikika cha chotupacho chimakhala ndi kuwonjezereka kosalekeza kolimbika kwa zizindikiro ndi zizindikiro zikufanana ndi matenda a hypertensive.
Nthendayi yokhala ndi mitundu yosiyanasiyana imayambitsa mavuto oopsa - ndi pheochromocytoma imayambitsa matenda otaya magazi mu retina wa diso, pulmonary edema kapena stroke.
Pheochromocytoma - matenda
Matendawa amapangidwa pambuyo pa mayeso angapo a ma laboratory:
- kuphunzira za magazi kuti zisamalire ma catecholamines, kukhalapo kwa leukocytosis, kuwonjezeka kwa ESR, hyperglycemia, erythrocytosis, eosonophilia;
- kuyambitsa mkodzo kwa kudziwika kwa cylindruria, proteinuria, glucosuria, aspretion ya vanillylmandelic acid;
- mayesero ogwira ntchito ndi histamine ndi reginal.
Zowonjezereka zitha kupezeka kudzera ku ultrasound ya adrenal glands , computed tomography, aortography, kujambula.
Tiyenera kukumbukira kuti pheochromocytoma ili ndi nthawi yokwanira yokwanira kuti azindikire matendawa nthawi ndi kuyamba mankhwala. Choncho, munthu aliyense amene akudwala matenda a hypertension amafunika kuyesedwa kuchipatala kuti asachotseretu chotupacho ngati chifukwa cha kuwonjezeka kwa magazi.
Pheochromocytoma - zovuta ndi matenda
Zotsatira zoipa zambiri zimakhalapo pakatha mavuto:
- myocardial infarction;
- kufalikira kwa ubongo;
- mpweya ;
- mtima kulephera.
Ngati palibe mankhwala oyenera, odwala, makamaka, amawonongeka.
Thandizo la panthaŵi yake komanso kuchotsa opaleshoni ya pheochromocytoma zimapangitsa kuti munthu adziwe bwino, makamaka ngati chotupacho sichili choipa ndipo palibe metastases. Monga momwe chiwonetsero chimasonyezera, kubwereranso kumachitika kokha mwa 5-10% mwa milandu, ndipo zowonjezera zowonongeka bwino zimasinthidwa ndi chithandizo cha mankhwala.