Imodzi mwa mankhwala otchuka kwambiri oletsa tizilombo toyambitsa matenda ndi immunomodulating, Interferon Alpha, ndi chipatso cha ma genetic. Zimachokera ku mapuloteni oyeretsedwa, omwe ndi analoji a mapuloteni a magazi ndipo amatchedwa interferon. Zitha kukhala zosiyana siyana, koma kukonzekera kwa mapuloteni a interferon alfa kumasiyana ndi bioavailability.
Fomu yotulutsira Interferon Alpha
Pali njira zambiri zogwiritsira ntchito mankhwalawa, kotero kumasulidwa kwa mitundu yosiyanasiyana ya mankhwala ndi mankhwala omveka bwino:
- Dothi wouma ntchito yogwiritsira ntchito jekeseni pamodzi ndi madzi osungunuka;
- njira yokonzekera yokonzekera jekeseni;
- zoperekera zamatsenga;
- mafuta;
- madontho a nasal;
- mpweya wamphongo;
- madontho a diso;
- ufa wouma chifukwa chokonzekera madontho a m'mphuno ndi maso.
Ntchito ya Interferon Alpha
Chithandizo ndi Interferon Alpha chimachokera pamtunda wothamanga kwambiri. Zakhala zikudziwika kale kuti munthu amene amachititsa kachilombo kamodzi m'thupi sangathe kutenga kachilombo ka mtundu wina. Pogwiritsa ntchito interferon, maselo omwe kachilombo ka HIV kamene sikanalowemo, amakhala osagonjetsedwa nawo ndipo pamapeto pake matendawa amatha. Popeza chiwembuchi n'choyenera kwa mavairasi a mtundu uliwonse, kusiyana kwa Interferon Alpha ndi kwakukulu kwambiri:
- chiwindi cha chiwindi cha mtundu uliwonse;
- conjunctivitis;
- matenda opatsirana ndi amphongo ndi ophthalmic;
- SARS , fuluwenza;
- mapiritsi a laryngeal;
- multiple myeloma;
- liwu;
- Kaposi sarcoma;
- lymphoma;
- katemera;
- mavairasi a bactericidal-mavairasi a mtundu uliwonse mwa ana.
Mosiyana ndi mankhwala ena oletsa tizilombo tosinthika, interferon ili ndi zochepa zosiyana. Amagwiritsidwa ntchito mosamala mukakumana ndi mavuto ndi ziwalo za excretion ndi matenda ena a chiwindi. Pakati pa mimba ndi lactation mankhwalawa amatengedwa mwatsatanetsatane malinga ndi mankhwala a dokotala. Zotsatira za Interferon Alpha sizingatchedwe zosangalatsa, koma n'zosavuta. Izi ndi izi:
- chills;
- malungo;
- chisokonezo;
- kugona.
Ndikofunika kudziwa kuti mankhwalawa sagwirizana kwambiri ndi mankhwala ena ndi mankhwala, kotero muyenera kufunsa wothandizira kugwiritsa ntchito aliyense wa iwo. Izi zidzakuthandizani kupewa mavuto aakulu. Ndikofunika kwambiri kutenga interferon pamodzi ndi mankhwala osokoneza bongo komanso mankhwala osokoneza bongo.
Momwe mungagwirire Interferon Alpha mu ufa, zimadalira zolinga. Mlingo woyenera wa mankhwalawo uyenera kuti ukhale woyeretsedwa kale ndi madzi osungunuka kuti mujekesedwe ndi kuchuluka kwa 50 ml. Ngati mukusowa madontho m'mphuno mwanu, kapena maso, mutha kugwiritsa ntchito saline (sodium chloride) chifukwa chaichi.
Dontho la diso la Interferon Alpha ndi mitundu ina ya mankhwala ndi okonzeka kugwiritsidwa ntchito ndipo safuna kuwonjezera kwa zigawo zina.
Zizindikiro za Interferon Alpha
Pakalipano, pali mankhwala ambiri omwe amachokera ku ma interferons osiyanasiyana. Zina mwazo ndizochokera kuzinthu zofunikira, zina zimachokera kumudzi, koma kukula kwake kwa mankhwala onsewa ndi ofanana. Kusiyana kokha ndi mtundu wa mapuloteni oyeretsa ndipo, chotero, mtengo. Nazi mndandanda wa mankhwala omwe angasinthe Interferon Alpha:
- Alfarekin;
- Chithandizo;
- Roferon;
- Chipatala;
- Vellveron;
- interferon leukocyte anthu ndi ena.
Mankhwala onsewa apangidwa kuti athetse mawonetseredwe a mavairasi osiyanasiyana, kuteteza kufalikira kwa thupi, kuteteza matenda a maselo atsopano, kulimbitsa maselo atsopano. Chifukwa cha kapangidwe ka mavitamini a mtundu wapadera, thupi limalimbitsa chitetezo cha mthupi ndipo limayamba kudziimira palokha polimbana ndi matenda. Komanso ma interferons a mitundu yonse ali ndi mphamvu zotsutsana, zomwe zimayambitsa zomwe sizinakonzedwenso kuti zikhale ndi chibwenzi, komabe kugwiritsa ntchito mankhwala ochizira komanso kupewa khansa siletsedwe.