Bisphosphonates pofuna kuchiza matenda otupa mafupa

Osteoporosis imaonedwa kuti ndi imodzi mwa matenda omwe amapezeka kwambiri m'misakani. Ndipo motero, pa njira za chithandizo, akatswiri ake ayenera kulingalira nthawi zambiri. Monga momwe adasonyezera, bisphosphonates pofuna kuchiza matenda odwala matenda a m'mimba ndi abwino komanso kuthekera. Gulu ili la mankhwala linadziwika kuti lichiritsidwa kuchokera pakati pa zaka za m'ma 1900, koma zinkatheka kupeza kufalikira kwaposachedwapa.

Mankhwala-bisphosphonates

Mankhwala ena a bisphosphonates akhala akugwiritsidwa ntchito kuteteza chitetezo. Nthawi zambiri ankagwiritsidwa ntchito m'mafakitale a mafuta ndi nsalu. Masiku ano bisphosphonates yatha kukhala maziko a mankhwala ozunguza bongo. Ndiwo phosphorous amchere, omwe amathandiza kuti mapangidwe apangidwe a mafupa apangidwe komanso kupewa chiwonongeko chake. Izi zikutanthauza kuti mankhwalawa akuwoneka kuti apangidwa kuti athetse matenda a mitsempha.

Kuwonjezera pa kulimbitsa, bisphosphonates imabweretsa zotsatira zowonongeka komanso zotsutsa. Chifukwa cha ichi, mankhwala a bisphosphonate amagwiritsidwa ntchito pa fractures ndi primary hyperparathyroidism. Ndipo kuthekera kwa kugwira ntchito pa maselo oopsa kumathandiza kuti mugwiritse ntchito mankhwala osokoneza bongo, kuphatikizapo kufooka kwa mphamvu ya fupa.

Ndi mankhwala ati a bisphosphonate omwe amagwiritsidwa ntchito pa osteoporosis?

Ma bisphosphonates onse angathe kukhala okhudzana ndi magulu awiri:

• omwe ali mu maonekedwe a nayitrogeni;
• opanda nitrogen.

Mndandanda wa mankhwala otchuka kwambiri ndi awa:

1. Bondronate imaperekedwa kuti azitha kuchiza komanso kupewa matenda odwala matenda a m'mimba. Mosiyana ndi mankhwala ena ofanana, Bondronate ingatengedwe ngakhale ndi amayi omwe akudwala mankhwala a mahomoni pa nthawi ya kusamba. Nthawi zina, mankhwalawa amaperekedwa kwa odwala omwe ali ndi hypercalcemia .
2. Bisphosphonate Ethidronate sodium imalamulidwa kuti azidwala matenda odwala matenda a m'mimba ndipo yatsimikiziridwa yokha pakuchiza matenda omwe achitika motsutsana ndi chikhalidwe cha oncology.
3. Acid clodronic amagwiritsidwa ntchito pofuna kuwononga macrophages. Izi zimayambitsa mankhwala osokoneza bongo.
4. Mankhwala Tiludronate amaperekedwa kwa odwala omwe ali ndi mafupa ofewa kwambiri kuti abwezeretse msinkhu wawo mofulumira.
5. Risedronate imateteza kuphulika kwa msana ndi khosi lachikazi - kuvulala kofala komwe kumachitika kwa amayi omwe akuwopsa.

Mbali za mankhwala a bisphosphonate

Ndikofunika kumvetsetsa kuti mafupa olimbikitsa si njira yofulumira kwambiri. Ngakhale kuti bisphosphonates amachita mofulumira, satha kuthetsa vutoli kwa masiku angapo. Choncho, kuyambira kuchipatala, wodwalayo ayenera kudzikonzekera yekha kuti maphunzirowo apitirire chaka. Kawirikawiri bisphosphonates amatenga zaka zingapo. Koma zotsatira za mankhwalawa zimakondweretsa kwambiri.

Awa ndiwo mankhwala amphamvu kwambiri. Zokonzekera zonse zomwe zili ndi bisphosphonates sizikuphulika bwino m'thupi. Choncho, kotero kuti mankhwala amathandizidwa bwino ndipo sapereka zotsatira, muyenera kutsatira malamulo ena ndi machenjezo:

1. Ndi bwino kumwa bisphosphonates m'mawa pa chopanda kanthu m'mimba osachepera ora ndi theka asanadye chakudya.
2. Ndibwino kuti muzimwa piritsi ndi madzi ambiri. Gwiritsani ntchito madzi ena (tiyi, madzi, mkaka) ndi osafunika kwambiri.
3. Kwa pulogalamuyo kunali kosavuta kuti tifikire komweko, titatha kutenga bwino kwa ola limodzi kapena hafu kukhala kapena kuima.

Kukonzekera kwakukulu kwambiri ndi mlingo wake uyenera kusankhidwa ndi katswiri pambuyo pa kafukufuku woyambirira.