Mankhwala osokoneza bongo - lembani

Mchitidwe wa magazi coagulation ukupitirira mu magawo angapo. Choyamba ndi mapangidwe a thromboplastin, chachiwiri ndi thrombin mapangidwe, ndipo lachitatu ndi fibrinogenesis. Kuyenda koyenera kwa gawo lililonse m'magazi ayenera kukhala anticoagulant. Ngati zakuthupi zakuthupi sizikwanira, ndiye zimatsatiridwa - mankhwala ali ndi jekeseni.

Zisonyezero za kugwiritsa ntchito antchito oletsa antiplatelet

Antiagreganty - mankhwala osokoneza bongo omwe amachititsa kuti magazi asamawonongeke. Malingana ndi njira yowonongeka, iwo agawidwa m'magulu awiri:

• chochita molunjika (heparinoids, heparin);
• Zochita zosadziwika (zochokera ku phenylidandione ndi oxicumini).

Masiku ano, palinso antiplatelet antchito a m'badwo watsopano - zosagwirizana. Iwo ali ndi mphamvu yoletsa ku aggregation mphamvu yamapiritsi.

Kusankhidwa kwa magulu onse a mankhwala kungakhale kaya payekha kapena palimodzi. Zizindikiro zazikulu zogwiritsiridwa ntchito kwa anticoagulants ndi zizindikiro za magazi osokoneza bongo (chiwerengero cha mthupi) ndi njira yothandizira kumalo osiyanasiyana. Wodwalayo akulimbikitsidwa kutenga mankhwalawa ngakhale ndi mankhwala opatsirana pogwiritsa ntchito mitsempha, chifukwa iyi ndi imodzi mwa njira zothandizira kupewa kutsekula kwapakati pamtundu wa myocardial .

Zotsutsana ndi ntchito ya antiplatelet agents

Mankhwala osakanikirana masiku ano sangathe kuuzidwa ngati wodwala ali ndi matenda:

• zipangizo zam'mimba (ngakhale m'mayendedwe a magazi);
• impso ndi zizindikiro za hematuria;
• chiwindi ndi kuwonongeka kwakukulu kwa ntchito yake.

Sitikulimbikitsidwa kutenga mankhwala a gululi ngati pali zizindikiro za impso zolephera, kuphwanya njira za haemostatic, kusowa kwa vitamini C-ndi K komanso mtima wamtima wamtima.

Mankhwalawa amachititsa zotsatira. Zimaonekera makamaka pogwiritsa ntchito antiticoagulants zachindunji kapena zosadziwika. Kusiyanasiyana kulibe vuto lililonse pa thupi.

Zotsatira zofala kwambiri za antiplatelet agents ndi:

• zosokoneza;
• mutu;
• zovuta zowonongeka;
• kutuluka magazi kwa malo ena.

List of antiplatelet agents

Mankhwala a antiticoagulants amathandizira mwachindunji zinthu za magazi coagulation mu kanjira kake. Zotsatira za kuchiritsidwa ndi jekeseni wa intravenous zimapezeka pafupifupi nthawi yomweyo ndipo zimakhala maola 6. Mndandanda wa othandizira antiplatelet a gulu ili akuphatikizapo:

• Heparinolds;
• Heparin;
• Arvin;
• Helicinate ya calcium;
• Chondroitin sulfates A ndi C.

Ambiri amagwiritsidwa ntchito ndi Heparin. Icho chimachepetsa msangamsanga mapangidwe a fibrin ndipo imalepheretsa agglutination wa mapulogalamu a magazi.

Mndandanda wa antigregregants wa ntchito yosalunjika umaphatikizapo:

• Dicoumarin;
• Cincumar;
• Nafarini;
• Neodikumarin;
• Phenylin;
• Omefin.

Amaletsa magazi kutsekemera kokha m'thupi. Zotsatira pambuyo pemapemphero zimabwera m'maola 24-72 ndikukhala masiku angapo. Ndi chifukwa cha malowa kuti mankhwalawa ndi othandizira kuti azitha kuchiritsidwa kwa nthawi yayitali.

Kusiyanitsa pakati pa magulu a antiplatelet amagwira malo apadera. Zonse mwakuti iwo alibe zotsatira pang'ono pa ntchito ya coagulation ya magazi. Koma panthawi imodzimodziyo amaletsa kapena kulepheretsa mapepalawo. Choncho, kuphatikizapo mankhwala ena ndi antiplatelet agents, iwo zosasinthika pofuna kupewa thrombosis ndi myocardial infarction. Kukonzekera kwa gululi ndi:

• Butadione;
• Papaverine ;
• Anturan;
• Indomethacin;
• Imizine;
• Carbocromene;
• Parmedin.

Zosagwirizana zonsezi ziyenera kuuzidwa kwa anthu okalamba ndi okalamba.