Pradaxa ndi mankhwala omwe ali m'gulu la mankhwala a antiticoagulant ndi antithrombotic. Amagwiritsira ntchito m'matumbo ndi m'matendawa m'malo operekera ntchito makamaka makamaka popewera tizilombo toyambitsa matenda.
Kukhoza kugwiritsa ntchito Pradax
Chofunika kwambiri cha mankhwalawa ndi dabigatran etexilate. Chifukwa cha ichi, ntchito ya thrombin imaletsedwa pambuyo polemba kukonzekera kwa Pradax. Dabigatran etexilate imadziwika mofulumira ndipo imasandulika kukhala dabigatran (mobwerezabwereza thrombin inhibitor) panthawi ya hydrolysis. Mphamvu ya mankhwala imachepetsedwa ndi 20% ngati kulemera kwa munthu kuliposa 120 makilogalamu, ndipo kumawonjezeka ndi 25% ndi kulemera kwa thupi kwa wodwala osachepera 48 kg.
Zisonyezo za ntchito Pradax ndi:
- kuteteza thromboembolism;
- kuteteza mitundu yosiyanasiyana ya thromboembolism ;
- kupewa matenda a mtima kwa odwala omwe amagwidwa ndi matenda a atrial.
Kugwiritsiridwa ntchito kwa Pradax kukuwonetsedwa kwa pafupifupi odwala onse omwe ali ndi matenda oterewa atatha kugwira ntchito, chifukwa cha zida zamakono zonsezi mankhwalawa akuwoneka kuti ndi othandiza kwambiri. Komanso, mankhwalawa amatumizidwa pambuyo pa bondo lomaliza endoprosthetics. Kulandila kuti thupi libwezere mwamsanga, liyenera kuyamba maola 1-4 pambuyo pa kutha kwa opaleshoniyo.
Zotsutsana ndi ntchito ya Pradaxi
Ngakhale muli ndi zizindikiro zogwiritsira ntchito mankhwala a Pradax, simungagwiritse ntchito mankhwalawa kwa hypersensitivity kwa zigawo zilizonse za mankhwala. Musayambe kugwiritsa ntchito mankhwalawa movuta kwambiri a impso kulephereka, mwadzidzidzi kapena kusokoneza vuto la homeostasis komanso matenda ochepa kwambiri a magazi.
Zotsutsana ndi ntchito ya Pradax ndizo:
- wosalimba chiwindi ntchito;
- kupweteka kwa msana ndi ubongo;
- zovuta zopweteka;
- kupweteka kwa magazi;
- m'mimba zilonda;
- intracerebral vascular disorders.
Sikoyenera kuti mugwiritse ntchito mankhwalawa panthawi imodzimodzimodzi ndi antiplatelet agents. Kuphatikizana kumeneku ndi koopsa pa moyo, chifukwa kumapangitsa kuti pakhale ngozi yoika magazi pafupifupi katatu. Ngati pali umboni wogwiritsira ntchito pradax ndi dokotalayo adaganiza zopereka mankhwalawa, ndiye kofunikira kuthetsa kudya kwa mitundu ina ya anticoagulants. Sitikulimbikitsidwa kuti tichite chithandizo ndi mankhwala otero kwa odwala osakwana zaka 18, popeza palibe deta ya zotsatira za ntchito yake m'badwo uno.