Thyroxine, mahomoni opangidwa ndi hypothalamus, ndi ofunika kwambiri poonetsetsa kuti ntchito ya chithokomiro imakhala yabwino. Zambiri mwa kachigawo ka hormone T4 sizigwirizana ndi mapuloteni othandizira, chifukwa chake dzina lake "free thyroxine" likufotokozedwa.
Mayeso a magazi kwa thyroxine yaulere
T4 imakhudza thupi la munthu motere:
- amachititsa kuti okosijeni azigwiritsa ntchito maselo;
- normalizes metabolism mu ziphuphu;
- amachotsa zotengera za cholesterol kwambiri;
- kumalimbikitsa kaphatikizidwe ka mapuloteni;
- amaletsa thrombosis;
- kuonetsetsa kuti chitukuko ndi kukula zikuchitika;
- imathandizira njira yopangira kutentha.
Kuphatikiza apo, ma hormone T4 amakhudza kuthekera kwa mayi kutenga mimba, kupirira ndi kubala mwana wathanzi. Mogwirizana ndi kufunikira kwa ma hormoni pa moyo wa thupi, m'pofunika kudziwa ngati mlingo wa thyroxine waufulu ndi wamba. Kuti mudziwe zambiri za thyroxine mumagazi a m'magazi mu labotale ndi zowononga magazi.
Chikhalidwe cha thyroxine yaulere chimadalira kugonana ndi msinkhu. Mwa amuna, zomwe zili m'thupi ndi zazikulu kuposa za akazi. Makhalidwe abwino a T4 mwa amayi ndi awa:
- ali ndi zaka zoyambira 14 mpaka 40 - 100-120 nM / l;
- pambuyo pa zaka 40 - 80-100 nM / l.
Mu amayi oyembekezera, thyroxin yaufulu ndi 120-140 nM / L, ndipo izi zimatheka chifukwa chakuti mbali imodzi ya mahomoni amapita ku mapangidwe a fupa la mwana. Kudalira kwa zomwe zili m'magazi T4 pa nthawi ya tsiku ndi nyengo ya chaka zinakhazikitsidwa.
Mtengo wapamwamba walembedwa:
- mu October ndi February;
- kuyambira 8:00 mpaka 12-00.
Mtengo wotsika ndi:
- mu June-August;
- kuyambira 23-00 mpaka 3-00.
Kuchulukitsa kwa thyroxine
Thyroxine yaulere yowonjezera ku:
- myeloma ;
- kupweteka kwa impso;
- Matenda a chiwindi, kuphatikizapo omwe ali ndi chiwindi;
- hypertrophic amasintha chithokomiro cha matenda a Based's disease ndi Graves;
- kuphwanya malamulo;
- kulemera kwa thupi.
Komanso, kuchuluka kwa ma hormone T4 kungatuluke chifukwa cha kudzipiritsa kwa matenda a mtima, osakwanira zochitika zina zamankhwala (Aspirin, Danazol, Levotheoxin, Furosemidonoma, etc.) ndi ntchito ya Heparin yosagwiritsidwa ntchito pa mankhwala a thrombosis.
Free thyroxine inatsika
Zomwe zili ndi thyroxin yaulere pansi pazimenezo zimakhala zofanana ndi zizindikiro ndi matenda monga:
- thupi;
- mapuloteni zakudya zowononga;
- zochitika zovuta nthawi yaitali;
- kusowa kwa ayodini;
- goiter;
- chithandizo ;
- zilonda zotentha za chithokomiro;
- kutukusira kwa ntchentche;
- chisokonezo;
- poizoni.
Nthawi zina kutsika kwa thyroxin kwaulere kumadziwika pamene mukumwa mankhwala, kuphatikizapo:
- kugwiritsa ntchito mankhwala osokoneza bongo kwambiri;
- Kuchulukanso kwa Mitsempha ndi mankhwala ena omwe amatsitsa magazi;
- kugwiritsa ntchito njira zothandizira kulera;
- kugwiritsa ntchito mankhwala oletsa TB, anti-inflammatory, antiticonvulsant mankhwala, glucocorticoids ndi mankhwala ochizira matenda oopsa a goiter.
Chonde chonde! Kuchepa kwa T4 kungasonyeze kuti wodwala akutenga mankhwala ozunguza mankhwala.
Pewani kusintha kwa zomwe muli thyroxine mumagazi - osati nthawi yodetsa nkhaŵa, koma kusintha kwadzidzidzi m'mkhalidwe wa mahomoni ndi kuwonongeka kwa mkhalidwe wa thanzi kumafuna mayeso ndi akatswiri. Choncho, kuti mudziwe kusintha kwa kusintha kwa msinkhu wa T4 mu matenda a chithokomiro, tikulimbikitsidwa kuti tipereke magazi katatu pa mwezi kwa zaka ziwiri.