Ngati mukudwala matenda a mphumu kapena a mphumu, dokotalayo angakulimbikitseni kugula Salbutamol Aerosol, yomwe idzathetseratu zowawa.
Pulogalamu ya piritsi ya Salbutamol
Mankhwalawa ndi bronchodilator ndi otchulidwa odana ndi zotupa. Chinthu chachikulu chimene chili mbali ya mankhwala ndi salbutamol. Kwa 100 mg ya mankhwala muli 0.0725 mg wa mankhwala awa. Zida zothandizira ndizo:
- chotsitsa cha cetyl;
- firimu;
- difluodichloromethane;
- oleic acid;
- ethanol.
Mchitidwe wa Salbutamol
Salbutamol chifukwa cha kupuma kwa thupi kumalimbikitsa beta2-adrenergic receptors pamtunda, komanso mitsempha ya magazi. Zimalepheretsa kumasulidwa kwa zinthu zamagetsi kuchokera ku maselo akuluakulu. Ntchito yake ndi yaitali. Komanso, mankhwalawa amachititsa kuti mapapu azikhala ofunika komanso amachititsa kuti maluwa asapangidwe. Ngati awonedwa ndi wodwalayo, ndiye kuti mankhwalawa amatha kuimitsa. Kugwiritsiridwa ntchito kwa mankhwala kumapangitsa kuti pakhale kusiyana pakati pa nkhwangwa, kumapangitsa ntchito ya maselo a ciliated epithelium. Mankhwalawa amaletsa kumasulidwa kwa histamine. Pogwiritsidwa ntchito, palibenso kuchepa kwa magazi.
Chifukwa chakuti ziwalozikulu za mankhwalawa zimathamangira kwambiri m'thupi ndi magazi, zotsatira zake zimamveka mwamsanga mutatha kugwiritsa ntchito. Mpumulo waukulu ukhoza kubwera mu mphindi 30-60. Zotsatira zimatha maola atatu.
Ndani amalimbikitsa salbutamol aerosol?
Salbutamol ali ndi zizindikiro zogwiritsidwa ntchito motere:
- Njira zolepheretsa (kutsekereza kapena kuperewera kwa lumin ya bronchi ndi emphysema ya mapapo ndi bronchitis);
- chifuwa chachikulu cha mphumu .
Kawirikawiri aerosol imagwiritsidwa ntchito ndi odwala omwe ali ndi asthmatic bronchitis, komanso omwe akuyenera kusiya bronchospasm.
Kuyanjana ndi mankhwala ena
Ndikoyenera kunena kuti puloteni ya salbutamol yosavomerezeka siyotchulidwa kuti iyanjanitsidwe ndi osasankha beta-adrenoreceptor blockers, mwachitsanzo, propranolol.
Theophylline ndi xanthine zingayambitse tachyarethmia, ndipo njira zowonjezereka za anesthesia ndizoopsa kwambiri za ventricular arrhythmias. Zizindikiro za pulogalamu ya piritsi zingathe kupangitsa kuti thupi liziyenda bwino, pamene mahomoni a chithokomiro angakhudze mkhalidwe wa mtima. Izi ziyenera kusamala ndi nthawi imodzi yosamalira mankhwala ophera anticholinergic, chifukwa izi zingayambe kuwonjezereka kwa kupanikizika kwa m'mimba.