Kukonzekera kwa glucocorticoid - mndandanda

Glucocorticoids ndi mtundu wa mahomoni opangidwa chifukwa cha ntchito ya adrenal cortex. Imodzi mwa mahomoni ndi cortisone, yomwe nthawi yomwe chiwindi chimayambira imakhala mtundu wina wa hydrocortisone (cortisol). Cortisol ndi hormone yotchuka komanso yofunika kwambiri kwa thupi la munthu. Mankhwala opangidwa ndi ma hormoni awa agwiritsidwa ntchito kuyambira zaka 40 zapitazo.

Mitundu ya mahomoni opangidwa

Pakali pano, kuwonjezera pa masoka a glucocorticoids, pali mankhwala angapo, makamaka pa mahomoni opangidwa, omwe amagawidwa mu mitundu iwiri:

• fluorinated (dexamethasone, betamethasone, etc.);
• osasindikizidwa (prednisone, prednisolone).

Iwo amadziwika kuti ndi opambana pamene akudya mlingo wapansi. Kuphatikiza apo, kutuluka kwa glucocorticoids kumakhala ndi zotsatira zochepa kwambiri za zotsatira.

Kugwiritsa ntchito mankhwala-glucocorticoids

Kukonzekera ndi zomwe zili ndi glucocorticoids, amagwiritsidwa ntchito pa matenda akuluakulu, tk. ali ndi zotsatira zosiyana pa thupi.

Mafupipafupi omwe amapanga mankhwalawa ndi awa:

• mphutsi yamoto ;
• nyamakazi ya nyamakazi;
• liwu;
• mononucleosis;
• Matenda a khungu (dermatitis, eczema);
• magazi;
• chibayo;
• matenda opatsirana;
• kupweteka;
• hepatitis.

Njira yowonekera sizimvetsetsedwa bwino, koma zotsatira za kugwiritsidwa ntchito kwa glucocorticoids zingakhale zotsutsa-kutupa, kuteteza thupi, kuteteza, kusokoneza. Kukonzekera kumaperekedwa m'njira zosiyanasiyana:

• kupopera;
• mapiritsi;
• lotions;
• mafuta;
• madzimadzi a jekeseni ndi inhalation.

Mndandanda wa mankhwala-glucocorticoids

Mndandanda wa njira zoterezi ndizambiri. Zotchuka kwambiri ndi zothandiza ndi izi:

• Cortisone - amagwira nawo ntchito yothandizira;
• Prednisolone - nthawi zoposa 4 kuposa Hydrocortisone;
• Prednisone - sichivomerezeka ku mavuto ndi chiwindi;
• Methylprednisolone - yoyenera kuchiza odwala olemera kwambiri, matenda ovutika maganizo, zilonda zam'mimba;
• Triamcinolone - imakhudza kwambiri kuposa prednisolone, yomwe imatulutsa zotsatira za minofu ndi khungu;
• Dexamethasone ndi kukonzekera kwa ntchito yaifupi;
• Betamethasone ndi mankhwala oyandikana ndi dexamethasone.

Zotsatira za glucocorticoids

Pogwiritsa ntchito mankhwala othandizira, glucocorticoids imakhala ndi zotsatira zochepa. Ndicho chifukwa chake nthawi zambiri amaikidwa ngati maphunziro amfupi kapena amagwiritsidwa ntchito pa milandu yovuta kwambiri. Kukonzekera kwa gulu la glucocorticoids kungayambitse zotsatirazi zosayenera:

• osteoporosis, mutu wachikazi wa necrosis;
• kupunduka kwa mafupa;
• kuchepetsa turgor khungu;
• maonekedwe a streaks, kuponda, kutaya magazi;
• kuwonjezeka kulemera kwa thupi;
• Kuphwanya ufulu wa maganizo;
• shuga;
• chiletso cha kutha msinkhu;
• Matenda a m'mimba (esophagitis, chapamimba ndi kutuluka pamimba).
• matenda ophthalmic ( glaucoma , cataract).